Stem-loop mmu-mir-154

Accession

MI0000176

Symbol

MGI: Mir154

Description

Mus musculus mmu-mir-154 precursor miRNA

Literature search

24 open access papers mention mmu-mir-154
(125 sentences)

Sequence

26487 reads, 320 reads per million, 72 experiments

gaagaUAGGUUAUCCGUGUUGCCUUCGcuuuauucgugacgAAUCAUACACGGUUGACCUAUUuuu
((((((((((((.((((((....(((((.........).))))....)))))).))))))))))))

Structure

            U      UGCC    - uuu 
gaagaUAGGUUA CCGUGU    UUCG c   a
|||||||||||| ||||||    |||| |   u
uuuUUAUCCAGU GGCACA    AAgc g   u
            U      UACU    a ugc 

Annotation confidence Medium

Genome context

chr12: 109738433-109738498 [+]

Clustered miRNAs

14 other miRNAs are < 10 kb from mmu-mir-154

Mature mmu-miR-154-5p

• Accession: MIMAT0000164
• Description: Mus musculus mmu-miR-154-5p mature miRNA
• Sequence: 6 - UAGGUUAUCCGUGUUGCCUUCG - 27
• Evidence: experimental ; cloned [1,3-4], PCR [2], Illumina [5-6]

Mature mmu-miR-154-3p

• Accession: MIMAT0004537
• Description: Mus musculus mmu-miR-154-3p mature miRNA
• Sequence: 42 - AAUCAUACACGGUUGACCUAUU - 63
• Evidence: experimental ; cloned [4], Illumina [5-6]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


3. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


6. PubMed ID: 15310658
   A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain
   "Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J"
   "Genome Res (2004) 14:1741-1748