Stem-loop mmu-mir-203

Accession

MI0000246

Symbol

MGI: Mir203

Description

Mus musculus mmu-mir-203 precursor miRNA mir-203

Gene
family

RF00696; mir-203

Literature search

103 open access papers mention mmu-mir-203
(758 sentences)

Sequence

193857 reads, 775 reads per million, 101 experiments

gccugguccAGUGGUUCUUGACAGUUCAACAguucuguagcacaauuGUGAAAUGUUUAGGACCACUAGacccggc
(((.((((.(((((((((.((((.((((.(((((.((...)).))))))))).)))).))))))))).)))).)))

Structure

   u    c         U    G    A     c  u 
gcc gguc AGUGGUUCU GACA UUCA CAguu ug  
||| |||| ||||||||| |||| |||| ||||| || a
cgg ccaG UCACCAGGA UUGU AAGU Guuaa ac  
   c    A         U    A    -     c  g 

Annotation confidence Low

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context

chr12: 112130880-112130955 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-203

Mature mmu-miR-203-5p

• Accession: MIMAT0004547
• Description: Mus musculus mmu-miR-203-5p mature miRNA
• Sequence: 10 - AGUGGUUCUUGACAGUUCAACA - 31
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-203-3p

• Accession: MIMAT0000236
• Description: Mus musculus mmu-miR-203-3p mature miRNA
• Sequence: 48 - GUGAAAUGUUUAGGACCACUAG - 69
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009