miRBase entry: mmu-mir-106b

Stem-loop mmu-mir-106b


Accession
MI0000407
Symbol
MGI: Mir106b
Description
Mus musculus mmu-mir-106b precursor miRNA
Gene family
MIPF0000001; mir-17

Literature search
113 open access papers mention mmu-mir-106b
(761 sentences)

Sequence

358667 reads, 2806 reads per million, 107 experiments
ccugcugggacUAAAGUGCUGACAGUGCAGAUagugguccucucugugcuaCCGCACUGUGGGUACUUGCUGCuccagcagg
(((((((((.(..(((((((.(((((((.....(((((.(.....).))))).))))))).)))))))...).)))))))))

Structure
         a -UA       G       AGAUa     c u 
ccugcuggg c   AAGUGCU ACAGUGC     guggu c c
||||||||| |   ||||||| |||||||     ||||| | u
ggacgaccu G   UUCAUGG UGUCACG     Caucg g c
         C UCG       G       ----C     u u 


Annotation confidence High
Do you think this miRNA is real?
Comments
Reference [1] reported the same miRNA sequence with two different identifiers - miR-106b and miR-94.

Genome context
chr5: 138165737-138165818 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from mmu-mir-106b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-106b-5p

Accession MIMAT0000386
Description Mus musculus mmu-miR-106b-5p mature miRNA
Sequence 12 - UAAAGUGCUGACAGUGCAGAU - 32
Evidence experimental
cloned [1-2], Illumina [3-4]
Database links
Predicted targets

Mature mmu-miR-106b-3p

Accession MIMAT0004582
Description Mus musculus mmu-miR-106b-3p mature miRNA
Sequence 52 - CCGCACUGUGGGUACUUGCUGC - 73
Evidence experimental
cloned [2], Illumina [3-4]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009