Accession
MI0000443
Symbol
HGNC:
MIR124-1
Description
Homo sapiens
hsa-mir-124-1 precursor miRNA
Literature search
429 open access papers mention hsa-mir-124-1
(3767 sentences)
(3767 sentences)
Sequence
97702
reads,
375
reads per million, 63 experiments
aggccucucucucCGUGUUCACAGCGGACCUUGAUuuaaauguccauacaauUAAGGCACGCGGUGAAUGCCAAgaauggggcug
.((((((..(((..((((((((.(((..((((((((.............))))))))..))).))))))))..)))..)))))).
.((((((..(((..((((((((.(((..((((((((.............))))))))..))).))))))))..)))..)))))).
Structure
a uc cC A GA uaaau ggccuc ucu GUGUUCAC GCG CCUUGAUu g |||||| ||| |||||||| ||| |||||||| u ucgggg agA CGUAAGUG CGC GGAAUuaa c g ua AC G AC cauac
Annotation confidence
High
Do you think this miRNA is real?
Comments
miR-124 was first identified by cloning studies in mouse [1]. Its expression was later verified in human embryonic stem cells [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [5]. The 5' end of the miRNA may be offset with respect to previous annotations.
Genome context
chr8: 9903388-9903472 [-]
Disease association
hsa-mir-124-1 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-124-5p
| Accession | MIMAT0004591 |
| Description | Homo sapiens hsa-miR-124-5p mature miRNA |
| Sequence | 14 - CGUGUUCACAGCGGACCUUGAU - 35 |
| Evidence |
experimental
cloned [5] |
Mature hsa-miR-124-3p
| Accession | MIMAT0000422 |
| Description | Homo sapiens hsa-miR-124-3p mature miRNA |
| Sequence | 53 - UAAGGCACGCGGUGAAUGCCAA - 74 |
| Evidence |
experimental
cloned [2,4-5] |
| Database links |
|
| Predicted targets |
|
References
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