miRBase entry: hsa-mir-137

Stem-loop hsa-mir-137

Homo sapiens hsa-mir-137 precursor miRNA
Gene family
MIPF0000106; mir-137

Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR137 is a gene that has been studied in relation to various diseases, including non-small-cell lung cancer [PMC4626561]. In a study, it was found that the methylation of MIR137 gene was correlated with the progression of non-small-cell lung cancer [PMC4626561]. Additionally, in another study, it was observed that the maximum peak outward potassium amplitude of VU0240551-treated MIR137 cKO neurons was adjusted to a similar level as wild-type neurons [PMC7237267]. These findings suggest that MIR137 may play a role in regulating potassium channels and neuronal activity. Further research is needed to fully understand the mechanisms and implications of MIR137 in disease progression and neuronal function.

Literature search
199 open access papers mention hsa-mir-137
(1747 sentences)


102896 reads, 1706 reads per million, 71 experiments

g u  u   --           ug   G             G      -  g 
 g cc cug  acucucuucgg  ACG GUAUUCUUGGGUG AUAAUa cg a
 | || |||  |||||||||||  ||| ||||||||||||| |||||| || u
 c gg gac  ugagaggagcu  UGC CAUAAGAAUUCGU UAUUgu gc u
a -  c   ca           GA   G             -      u  a 

Annotation confidence High
Do you think this miRNA is real?
This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context
chr1: 98046070-98046171 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-137
Name Accession Chromosome Start End Strand Confidence

Disease association
hsa-mir-137 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID

Biological pathways
hsa-mir-137 is involved in one or more biological pathways:
(Source: Reactome)
Biological reactions
hsa-mir-137 is involved in one or more regulation/signalling events:
(Source: Reactome)

Database links

Mature hsa-miR-137-3p

Accession MIMAT0000429
Description Homo sapiens hsa-miR-137-3p mature miRNA
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-137-5p

Accession MIMAT0037310
Description Homo sapiens hsa-miR-137-5p mature miRNA
Evidence not_experimental


  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739