Stem-loop hsa-mir-126

Accession

MI0000471

Symbol

HGNC: MIR126

Description

Homo sapiens hsa-mir-126 precursor miRNA mir-126

Gene
family

RF00701; mir-126

Literature search

445 open access papers mention hsa-mir-126
(2777 sentences)

Sequence

718134 reads, 2785 reads per million, 135 experiments

cgcuggcgacgggaCAUUAUUACUUUUGGUACGCGcugugacacuucaaacUCGUACCGUGAGUAAUAAUGCGccguccacggca
.((((..(((((..(((((((((((.(((((((.....(((....)))....))))))).)))))))))))..)))))..)))).

Structure

c    gc     ga           U       CGcug   c 
 gcug  gacgg  CAUUAUUACUU UGGUACG     uga a
 ||||  |||||  ||||||||||| |||||||     |||  
 cggc  cugcc  GUAAUAAUGAG GCCAUGC     acu c
a    ac     GC           U       -Ucaa   u 

Annotation confidence High

Genome context

chr9: 136670602-136670686 [+]

Disease association

hsa-mir-126 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-126-5p

• Accession: MIMAT0000444
• Description: Homo sapiens hsa-miR-126-5p mature miRNA
• Sequence: 15 - CAUUAUUACUUUUGGUACGCG - 35
• Evidence: experimental ; cloned [2]

Mature hsa-miR-126-3p

• Accession: MIMAT0000445
• Description: Homo sapiens hsa-miR-126-3p mature miRNA
• Sequence: 52 - UCGUACCGUGAGUAAUAAUGCG - 73
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739