Stem-loop hsa-mir-190a

Accession

MI0000486

Symbol

HGNC: MIR190A

Description

Homo sapiens hsa-mir-190a precursor miRNA

Literature search

43 open access papers mention hsa-mir-190a
(214 sentences)

Sequence

8022 reads, 33 reads per million, 94 experiments

ugcaggccucugugUGAUAUGUUUGAUAUAUUAGGUuguuauuuaauccaaCUAUAUAUCAAACAUAUUCCUacagugucuugcc
.(((((.(.(((((.((((((((((((((((..(((((..........)))))))))))))))))))))..))))).).))))).

Structure

u     c u     -U                UA     uuau 
 gcagg c cugug  GAUAUGUUUGAUAUAU  GGUug    u
 ||||| | |||||  ||||||||||||||||  |||||     
 cguuc g gacaU  UUAUACAAACUAUAUA  UCaac    u
c     u u     CC                --     cuaa 

Annotation confidence High

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

chr15: 62823957-62824041 [+]

Disease association

hsa-mir-190a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-190a-5p

• Accession: MIMAT0000458
• Description: Homo sapiens hsa-miR-190a-5p mature miRNA
• Sequence: 15 - UGAUAUGUUUGAUAUAUUAGGU - 36
• Evidence: experimental ; cloned [2], Illumina [3]

Mature hsa-miR-190a-3p

• Accession: MIMAT0026482
• Description: Homo sapiens hsa-miR-190a-3p mature miRNA
• Sequence: 52 - CUAUAUAUCAAACAUAUUCCU - 72
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45