Accession
MI0000489
Symbol
HGNC:
MIR195
Description
Homo sapiens
hsa-mir-195 precursor miRNA mir-15
Gene
family?
family?
RF00455;
mir-15
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR195 is a subset of miRNAs that has been studied in relation to its expression in MIN6B1 cells and rat pancreatic islets. Agarose gel electrophoresis was conducted at different N/P ratios to confirm the condensation of MIR195 with FasudilSHPMIR195 [PMC4990390]. The expression of MIR195, along with other miRNAs such as miR34a, miR96, miR145, miR146, and miR210, was further analyzed using quantitative RT-PCR in a large series of samples obtained from MIN6B1 cells and freshly isolated rat pancreatic islets [PMC2551683]. References: - [PMC4990390]: The reference provides information on the agarose gel electrophoresis conducted at different N/P ratios to confirm the condensation of MIR195 with FasudilSHPMIR195. - [PMC2551683]: The reference provides information on the analysis of the expression of MIR195 and other miRNAs using quantitative RT-PCR in samples obtained from MIN6B1 cells and rat pancreatic islets.
Literature search
231 open access papers mention hsa-mir-195
(1860 sentences)
(1860 sentences)
Sequence
191769
reads,
1198
reads per million, 153 experiments
agcuucccuggcucUAGCAGCACAGAAAUAUUGGCacagggaagcgagucugCCAAUAUUGGCUGUGCUGCUCCaggcaggguggug
.(((.(((((.((..((((((((((.((((((((((..((........))))))))))))..))))))))))..)).))))).))).
.(((.(((((.((..((((((((((.((((((((((..((........))))))))))))..))))))))))..)).))))).))).
Structure
a u g cU -A ca gaa gcu cccug cu AGCAGCACAG AAUAUUGGCa gg g ||| ||||| || |||||||||| |||||||||| || ugg gggac ga UCGUCGUGUC UUAUAACCgu cu c g u g CC GG -- gag
Annotation confidence
High
Do you think this miRNA is real?
Comments
This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].
Genome context
chr17: 7017615-7017701 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-195
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-195 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-195-5p
| Accession | MIMAT0000461 |
| Description | Homo sapiens hsa-miR-195-5p mature miRNA |
| Sequence | 15 - UAGCAGCACAGAAAUAUUGGC - 35 |
| Evidence |
experimental
cloned [2] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-195-3p
| Accession | MIMAT0004615 |
| Description | Homo sapiens hsa-miR-195-3p mature miRNA |
| Sequence | 53 - CCAAUAUUGGCUGUGCUGCUCC - 74 |
| Evidence |
experimental
cloned [2] |
References
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