Accession
MI0000774
Symbol
HGNC:
MIR302D
Description
Homo sapiens
hsa-mir-302d precursor miRNA
Gene family
MIPF0000071;
mir-302
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR302D is a member of the miR-302 family, which includes mature miRNAs encoded by genes MIR302A, MIR302B, MIR302C, and MIR302D [PMC5906557]. In morphine-treated organoids, the levels of miR186, miR181a, and MIR302D were increased [PMC8225561]. Let7c-5p potentially targets IL-6 and TLR4; IL-1α is a predicted target of miR181a and miR410; several microRNAs including MIR302D potentially regulate the expression of IL-25 [PMC8225561]. c-Jun is identified as a potential upstream transcript factor for MIR302D [PMC5906557]. The regulatory role of c-Jun on MIR302D expression is implied in the study [PMC5906557]. MiR-302d-3p is the mature miRNA encoded by the MIR302D gene located on 4q25 [PMC5906557]. The study used SP600125 and anisomycin to suppress or promote the JNK pathway and c-Jun activation to investigate their effect on MIR302D expression [PMC5906557]. MIR302D is highly expressed in both pluripotent stem cells and multipotent progenitor cells [PMC5966391]. MIR302D is one of the upregulated genes associated with the inhibition of endothelial cell migration and proliferation in ESRD-hiPSC-ECs [PMC8685359].
Literature search
182 open access papers mention hsa-mir-302d
(929 sentences)
(929 sentences)
Sequence
33
reads,
4
reads per million, 9 experiments
ccucuACUUUAACAUGGAGGCACUUGCugugacaugacaaaaaUAAGUGCUUCCAUGUUUGAGUGUgg
((..(((((.((((((((((((((((.(((......)))....)))))))))))))))).))))).))
((..(((((.((((((((((((((((.(((......)))....)))))))))))))))).))))).))
Structure
uc U ---C ga cc uACUU AACAUGGAGGCACUUG ugu c || ||||| |||||||||||||||| ||| gg GUGAG UUGUACCUUCGUGAAU aca a -U U aaaa gu
Annotation confidence
Not enough data
Do you think this miRNA is real?
Comments
Human miR-302a (MIR:MI0000738), miR-302b (MIR:MI0000772), miR-302c (MIR:MI0000773), miR-302d (MIR:MI0000774) and miR-367 (MIR:MI0000775) are clustered on chromosome 4.
Genome context
chr4: 112648004-112648071 [-]
Clustered miRNAs
4 other miRNAs are < 10 kb from hsa-mir-302d
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature hsa-miR-302d-5p
| Accession | MIMAT0004685 |
| Description | Homo sapiens hsa-miR-302d-5p mature miRNA |
| Sequence | 6 - ACUUUAACAUGGAGGCACUUGC - 27 |
| Evidence |
experimental
cloned [2] |
Mature hsa-miR-302d-3p
| Accession | MIMAT0000718 |
| Description | Homo sapiens hsa-miR-302d-3p mature miRNA |
| Sequence | 44 - UAAGUGCUUCCAUGUUUGAGUGU - 66 |
| Evidence |
experimental
cloned [1-2], Northern [1] |
| Database links |
|
| Predicted targets |
|
References
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