Stem-loop hsa-mir-346

Accession

MI0000826

Symbol

HGNC: MIR346

Description

Homo sapiens hsa-mir-346 precursor miRNA mir-346

Gene
family

RF00758; mir-346

Literature search

38 open access papers mention hsa-mir-346
(440 sentences)

Sequence

532 reads, 7 reads per million, 60 experiments

ggucucuguguugggcgucUGUCUGCCCGCAUGCCUGCCUCUcuguugcucugaaggaggcaggggcugggccugcagcugccugggcagagcgg
.(.((((((..((((((.((((..((((((...((((((((.((..........)))))))))).)).))))..)))).)))))).)))))))..

Structure

-g u      gu      u    CU    -  AUG        U  guug 
  g cucugu  ugggcg cUGU  GCCC GC   CCUGCCUC cu    c
  | ||||||  |||||| ||||  |||| ||   |||||||| ||     
  c gagacg  guccgu gacg  cggg cg   ggacggag ga    u
gg -      -g      c    uc    u  --g        -  aguc 

Annotation confidence Not enough data

Comments

This sequence is the predicted human homologue [2] of a sequence cloned from rat neuronal tissue [1]. The mature miRNA differs from the rat sequence at two positions, and its expression has not been verified in human.

Genome context

chr10: 86264694-86264788 [-]

Disease association

hsa-mir-346 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-346

• Accession: MIMAT0000773
• Description: Homo sapiens hsa-miR-346 mature miRNA
• Sequence: 20 - UGUCUGCCCGCAUGCCUGCCUCU - 42
• Evidence: not_experimental

References

1. PubMed ID: 15634332
   New human and mouse microRNA genes found by homology search
   "Weber MJ"
   "FEBS J (2005) 272:59-73


2. PubMed ID: 14691248
   Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
   "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
   "Proc Natl Acad Sci U S A (2004) 101:360-365