miRBase entry: hsa-mir-346

Stem-loop hsa-mir-346


Accession
MI0000826
Symbol
HGNC: MIR346
Description
Homo sapiens hsa-mir-346 precursor miRNA mir-346
Gene
family?
RF00758; mir-346

Literature search
109 open access papers mention hsa-mir-346
(629 sentences)

Sequence

795 reads, 11.0 reads per million, 75 experiments
ggucucuguguugggcgucUGUCUGCCCGCAUGCCUGCCUCUcuguugcucugaaggAGGCAGGGGCUGGGCCUGCAGCugccugggcagagcgg
.(.((((((..((((((.((((..((((((...((((((((.((..........)))))))))).)).))))..)))).)))))).)))))))..

Structure
-g u      gu      u    CU    -  AUG        U  guug 
  g cucugu  ugggcg cUGU  GCCC GC   CCUGCCUC cu    c
  | ||||||  |||||| ||||  |||| ||   |||||||| ||     
  c gagacg  guccgu GACG  CGGG CG   GGACGGAg ga    u
gg -      -g      C    UC    U  --G        -  aguc 


Annotation confidence High
Do you think this miRNA is real?
Comments
This sequence is the predicted human homologue [2] of a sequence cloned from rat neuronal tissue [1]. The mature miRNA differs from the rat sequence at two positions, and its expression has not been verified in human.

Genome context
chr10: 86264694-86264788 [-]

Disease association
hsa-mir-346 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-346-5p

Accession MIMAT0000773
Description Homo sapiens hsa-miR-346-5p mature miRNA
Sequence 20 - UGUCUGCCCGCAUGCCUGCCUCU - 42
Evidence not_experimental
Database links
Predicted targets

Mature hsa-miR-346-3p

Accession MIMAT0050497
Description Homo sapiens hsa-miR-346-3p mature miRNA
Sequence 58 - AGGCAGGGGCUGGGCCUGCAGC - 79
Evidence not_experimental

References

  1. PubMed ID: 15634332
    New human and mouse microRNA genes found by homology search
    "Weber MJ"
    "FEBS J (2005) 272:59-73

  2. PubMed ID: 14691248
    Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
    "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
    "Proc Natl Acad Sci U S A (2004) 101:360-365