miRBase entry: rno-mir-7a-2

Stem-loop rno-mir-7a-2


Accession
MI0000836
Description
Rattus norvegicus rno-mir-7a-2 precursor miRNA
Gene family
MIPF0000022; mir-7

Literature search
42 open access papers mention rno-mir-7a-2
(249 sentences)

Sequence

47645 reads, 82 reads per million, 459 experiments
ggacagaccagcccugucUGGAAGACUAGUGAUUUUGUUGUugugucuguguccaaCAACAAGUCCCAGUCUGCCACAugguguuggucacauca
.....(((((((.((((.(((.(((((.(.(((((.(((((((.(.......)))))))))))))).))))).))).)))).)))))))......

Structure
-ggaca       c    c   A     A U     U       u uc 
      gaccagc cugu UGG AGACU G GAUUU GUUGUug g  u
      ||||||| |||| ||| ||||| | ||||| ||||||| |  g
      cugguug gguA ACC UCUGA C CUGAA CAACaac c  u
acuaca       u    C   G     C -     -       - ug 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr1: 140576396-140576490 [+]

Database links

Mature rno-miR-7a-5p

Accession MIMAT0000606
Description Rattus norvegicus rno-miR-7a-5p mature miRNA
Sequence 19 - UGGAAGACUAGUGAUUUUGUUGU - 41
Evidence experimental
cloned [1-2], SOLiD [3]

Mature rno-miR-7a-2-3p

Accession MIMAT0017091
Description Rattus norvegicus rno-miR-7a-2-3p mature miRNA
Sequence 57 - CAACAAGUCCCAGUCUGCCACA - 78
Evidence experimental
SOLiD [3]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  3. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68