Stem-loop rno-mir-17-1

Accession

MI0000845

Description

Rattus norvegicus rno-mir-17-1 precursor miRNA

Gene family

MIPF0000001; mir-17

Literature search

72 open access papers mention rno-mir-17-1
(577 sentences)

Sequence

84499 reads, 120 reads per million, 495 experiments

gucaggauaauguCAAAGUGCUUACAGUGCAGGUAGuggugugugcaucuACUGCAGUGAAGGCACUUGUGGcauugugcugac
(((((.(((((((((((((((((.((.(((((.(((((.......)).)))))))).)).)))))))).))))))))).)))))

Structure

     g         -        A  G     G   -  gu 
gucag auaauguCA AAGUGCUU CA UGCAG UAG ug  g
||||| ||||||||| |||||||| || ||||| ||| ||  u
caguc uguuacGGU UUCACGGA GU ACGUC Auc ac  g
     g         G        A  G     -   u  gu 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr15: 100179879-100179962 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from rno-mir-17-1

Mature rno-miR-17-5p

• Accession: MIMAT0000786
• Description: Rattus norvegicus rno-miR-17-5p mature miRNA
• Sequence: 14 - CAAAGUGCUUACAGUGCAGGUAG - 36
• Evidence: experimental ; cloned [1-2], SOLiD [3]

Mature rno-miR-17-1-3p

• Accession: MIMAT0004710
• Description: Rattus norvegicus rno-miR-17-1-3p mature miRNA
• Sequence: 51 - ACUGCAGUGAAGGCACUUGUGG - 72
• Evidence: experimental ; cloned [2], SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


3. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68