Stem-loop hsa-mir-448

Accession

MI0001637

Symbol

HGNC: MIR448

Description

Homo sapiens hsa-mir-448 precursor miRNA

Gene family

MIPF0000149; mir-448

Literature search

36 open access papers mention hsa-mir-448
(236 sentences)

Sequence

34 reads, 6 reads per million, 12 experiments

gccgggagguugaacauccugcauagugcugccaggaaaucccuauuucauauaagagggggcuggcuggUUGCAUAUGUAGGAUGUCCCAUcucccagcccacuucguca
((.(((((((.(.((((((((((((.(((.(((((....(((((.((......)).))))).....))))).))))))))))))))).).))))))).))...........

Structure

-----------  c       u a            g   u     -gaaa     a  uc 
           gc gggaggu g acauccugcaua ugc gccag     ucccu uu  a
           || ||||||| | |||||||||||| ||| |||||     ||||| ||   
           cg cccucUA C UGUAGGAUGUAU ACG Ugguc     gggga aa  u
acugcuucacc  a       C C            -   U     ggucg     g  ua 

Annotation confidence Not enough data

Comments

Xie et al. [1] refer to this sequence by the internal identifier MIR64. The sequence is unrelated to C. elegans mir-64 (MIR:MI0000035).

Genome context

chrX: 114823454-114823564 [+]

Disease association

hsa-mir-448 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-448

• Accession: MIMAT0001532
• Description: Homo sapiens hsa-miR-448 mature miRNA
• Sequence: 71 - UUGCAUAUGUAGGAUGUCCCAU - 92
• Evidence: experimental ; cloned [1]

References

1. PubMed ID: 15735639
   Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
   "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
   "Nature (2005) 434:338-345