miRBase entry: hsa-mir-431

Stem-loop hsa-mir-431

Accession

MI0001721

Symbol

HGNC: MIR431

Description

Homo sapiens hsa-mir-431 precursor miRNA mir-431

Gene
family?

RF00718; mir-431

Literature search

28 open access papers mention hsa-mir-431
(46 sentences)

Sequence

2041 reads, 5 reads per million, 55 experiments

uccugcuuguccugcgaggUGUCUUGCAGGCCGUCAUGCAggccacacugacgguaacguugCAGGUCGUCUUGCAGGGCUUCUcgcaagacgacauccucaucaccaacgacg
...((.(((((.(((((((.((((((((((.((.(.((((((((........)))....))))).).)).)))))))))).))))))).)))))))..................

Structure

---------------ucc  c     c       U          C  U A     ----   aca 
                  ug uuguc ugcgagg GUCUUGCAGG CG C UGCAg    gcc   c
                  || ||||| ||||||| |||||||||| || | |||||    |||    
                  ac agcag acgcUCU CGGGACGUUC GC G ACguu    ugg   u
gcagcaaccacuacuccu  -     a       U          U  U G     gcaa   cag

Annotation confidence Not enough data

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Genome context

chr14: 100881007-100881120 [+]

Clustered miRNAs

6 other miRNAs are < 10 kb from hsa-mir-431

Name	Accession	Chromosome	Start	End	Strand	Confidence

Disease association

hsa-mir-431 is associated with one or more human diseases in the Human microRNA Disease Database

Disease	Description	Category	PubMed ID

Database links

Mature hsa-miR-431-5p

Accession	MIMAT0001625
Description	Homo sapiens hsa-miR-431-5p mature miRNA
Sequence	20 - UGUCUUGCAGGCCGUCAUGCA - 40
Evidence	experimental cloned [1-2]
Database links
Predicted targets

Mature hsa-miR-431-3p

Accession	MIMAT0004757
Description	Homo sapiens hsa-miR-431-3p mature miRNA
Sequence	63 - CAGGUCGUCUUGCAGGGCUUCU - 84
Evidence	experimental cloned [2]
Database links
Predicted targets

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414

PubMed ID: 15891114
Clustering and conservation patterns of human microRNAs
"Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H"
"Nucleic Acids Res (2005) 33:2697-2706