Stem-loop hsa-mir-433

Accession

MI0001723

Symbol

HGNC: MIR433

Description

Homo sapiens hsa-mir-433 precursor miRNA mir-433

Gene
family

RF00748; mir-433

Literature search

75 open access papers mention hsa-mir-433
(576 sentences)

Sequence

5947 reads, 81 reads per million, 107 experiments

ccggggagaagUACGGUGAGCCUGUCAUUAUUCagagaggcuagauccucuguguugagaaggAUCAUGAUGGGCUCCUCGGUGUucuccagg
((..((((((...(((.(((((((((((.(((((.(((((......))))).))........))).))))))))))).)))...)))))).))

Structure

  gg      gUA   U           U   --------  g     cu 
cc  ggagaa   CGG GAGCCUGUCAU AUU        Ca agagg  a
||  ||||||   ||| ||||||||||| |||        || |||||   
gg  ccucuU   GCU CUCGGGUAGUA UAg        gu ucucc  g
  -a      GUG   C           C   gaagaguu  g     ua 

Annotation confidence High

Genome context

chr14: 100881886-100881978 [+]

Clustered miRNAs

6 other miRNAs are < 10 kb from hsa-mir-433

Disease association

hsa-mir-433 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-433-3p

• Accession: MIMAT0001627
• Description: Homo sapiens hsa-miR-433-3p mature miRNA
• Sequence: 64 - AUCAUGAUGGGCUCCUCGGUGU - 85
• Evidence: experimental ; cloned [1-2], Illumina [3]

Mature hsa-miR-433-5p

• Accession: MIMAT0026554
• Description: Homo sapiens hsa-miR-433-5p mature miRNA
• Sequence: 12 - UACGGUGAGCCUGUCAUUAUUC - 33
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15891114
   Clustering and conservation patterns of human microRNAs
   "Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H"
   "Nucleic Acids Res (2005) 33:2697-2706


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45