Stem-loop ppy-mir-127

Accession

MI0002584

Description

Pongo pygmaeus ppy-mir-127 precursor miRNA

Sequence

ugugaucacugucuccagccugcugaagcucagagggcucugauucagaaagaucaUCGGAUCCGUCUGAGCUUGGCUggucggaagucucaucauc
.(((((.(((...(((.(((.(((.(((((((((.((.((((((((.....))..)))))).)).)))))))))))).))).))))))...))))).

Structure

u     --c   guc   a   u   g         g  c      --  a 
 gugau   acu   ucc gcc gcu aagcucaga gg ucugau  uc g
 |||||   |||   ||| ||| ||| ||||||||| || ||||||  || a
 uacua   uga   agg ugg CGG UUCGAGUCU CC AGGCUa  ag a
c     cuc   ---   c   U   -         G  U      cu  a 

Annotation confidence Low

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr14: 102428359-102428455 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from ppy-mir-127

Mature ppy-miR-127

• Accession: MIMAT0002283
• Description: Pongo pygmaeus ppy-miR-127 mature miRNA
• Sequence: 57 - UCGGAUCCGUCUGAGCUUGGCU - 78
• Evidence: not_experimental

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24