Stem-loop mml-mir-124a-1

Accession

MI0002766

Description

Macaca mulatta mml-mir-124a-1 precursor miRNA

Gene family

MIPF0000021; mir-124

Literature search

1 open access papers mention mml-mir-124a-1
(2 sentences)

Sequence

386912 reads, 2479 reads per million, 9 experiments

aucaagaucagaggcucugcccuccguGUUCACAGCGGACCUUGAUuuaaugucauacaaUUAAGGCACGCGGUGAAUGCCAagagcggagccuacggcugcacuugaa
.(((((..((((((((((((.((..((((((((.(((..((((((((...........))))))))..))).))))))))..)).)))))))))....)))..))))).

Structure

a     au   ----         c  cc        A   GA        uaau 
 ucaag  cag    aggcucugc cu  guGUUCAC GCG  CCUUGAUu    g
 |||||  |||    ||||||||| ||  |||||||| |||  ||||||||    u
 aguuc  guc    uccgaggcg ga  CGUAAGUG CGC  GGAAUUaa    c
a     ac   ggca         a  AC        G   AC        caua 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context

chr8: 62428637-62428745 [+]

Mature mml-miR-124a-3p

• Accession: MIMAT0002470
• Description: Macaca mulatta mml-miR-124a-3p mature miRNA
• Sequence: 61 - UUAAGGCACGCGGUGAAUGCCA - 82
• Evidence: experimental ; Illumina [2]

Mature mml-miR-124a-5p

• Accession: MIMAT0026585
• Description: Macaca mulatta mml-miR-124a-5p mature miRNA
• Sequence: 28 - GUUCACAGCGGACCUUGAU - 46
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68


2. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45