miRBase entry: ppy-mir-181b

Stem-loop ppy-mir-181b


Accession
MI0002936
Description
Pongo pygmaeus ppy-mir-181b precursor miRNA


Sequence

ccugugcagagauuauuguuuaaaaggucacaaucAACAUUCAUUGCUGUCGGUGGGUugaacuguguggacaagcucacugaacaaugaaugcaacuguggccccgcuu
.........................(((((((.....(((((((((...((((((((((....(((....))))))))))))).)))))))))....)))))))......

Structure
ccugugcagagauuauuguuuaaaa       aucAA         CUG          gaac   g 
                         ggucaca     CAUUCAUUG   UCGGUGGGUu    ugu u
                         |||||||     |||||||||   ||||||||||    |||  
                         ccggugu     guaaguaac   agucacucga    aca g
-------------------uucgcc       -caac         --a          ----   g 


Annotation confidence Not enough data
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context
chr1: 51520745-51520854 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from ppy-mir-181b
Name Accession Chromosome Start End Strand Confidence




Database links

Mature ppy-miR-181b

Accession MIMAT0002628
Description Pongo pygmaeus ppy-miR-181b mature miRNA
Sequence 36 - AACAUUCAUUGCUGUCGGUGGGU - 58
Evidence not_experimental

References

  1. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24