Stem-loop mml-mir-19a

Accession

MI0003003

Description

Macaca mulatta mml-mir-19a precursor miRNA

Literature search

12 open access papers mention mml-mir-19a
(16 sentences)

Sequence

105187 reads, 234.0 reads per million, 145 experiments

gcaguccucuguuAGUUUUGCAUAGUUGCACUAcaagaagaauguaguUGUGCAAAUCUAUGCAAAACUGAUgguggccugc
((((.((.(((((((((((((((((((((((((((.......))))...))))))..))))))))))))))))).)).))))

Structure

    u  u                 --      ---    ag 
gcag cc cuguuAGUUUUGCAUAG  UUGCAC   UAca  a
|||| || |||||||||||||||||  ||||||   ||||  a
cguc gg ggUAGUCAAAACGUAUC  AACGUG   augu  g
    c  u                 UA      Uug    aa 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

17: 73152399-73152480 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from mml-mir-19a

Mature mml-miR-19a-5p

• Accession: MIMAT0026596
• Description: Macaca mulatta mml-miR-19a-5p mature miRNA
• Sequence: 14 - AGUUUUGCAUAGUUGCACUA - 33
• Evidence: experimental ; Illumina [2]

Mature mml-miR-19a-3p

• Accession: MIMAT0002703
• Description: Macaca mulatta mml-miR-19a-3p mature miRNA
• Sequence: 49 - UGUGCAAAUCUAUGCAAAACUGAU - 72
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45