miRBase entry: ppy-mir-25

Stem-loop ppy-mir-25

Accession

MI0003069

Description

Pongo pygmaeus ppy-mir-25 precursor miRNA

Sequence

ggccaguguugagaggcggagacuugggcaauugcuggacgcugcccugggCAUUGCACUUGUCUCGGUCUGAcagugccggcc
((((.((((((..((((.(((((..(.(((((..((((........))))..))))).)..))))).))))..)))))).))))

Structure

    a      ag    g     uu g     ug    acg 
ggcc guguug  aggc gagac  g gcaau  cugg   c
|||| ||||||  |||| |||||  | |||||  ||||    
ccgg cgugac  UCUG CUCUG  C CGUUA  gguc   u
    c      AG    G     UU A     Cg    ccg

Annotation confidence Not enough data

Do you think this miRNA is real?

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr7: 9078853-9078936 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from ppy-mir-25

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature ppy-miR-25

Accession	MIMAT0002768
Description	Pongo pygmaeus ppy-miR-25 mature miRNA
Sequence	52 - CAUUGCACUUGUCUCGGUCUGA - 73
Evidence	not_experimental

References

PubMed ID: 15652478
Phylogenetic shadowing and computational identification of human microRNA genes
"Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
"Cell (2005) 120:21-24