Stem-loop hsa-mir-495

Accession

MI0003135

Symbol

HGNC: MIR495

Description

Homo sapiens hsa-mir-495 precursor miRNA mir-329

Gene
family

RF04295; mir-329

Literature search

50 open access papers mention hsa-mir-495
(177 sentences)

Sequence

10128 reads, 41 reads per million, 102 experiments

ugguaccugaaaaGAAGUUGCCCAUGUUAUUUUCGcuuuauaugugacgAAACAAACAUGGUGCACUUCUUuuucgguauca
(((((((.((((((((((.(((((((((..((((((.........).)))))..))))))).)))))))))))).)))))))

Structure

       u          U  -       AU     - uuu 
ugguacc gaaaaGAAGU GC CCAUGUU  UUUCG c   a
||||||| |||||||||| || |||||||  ||||| |   u
acuaugg uuuUUCUUCA CG GGUACAA  AAAgc g   a
       c          -  U       AC     a ugu 

Annotation confidence High

Genome context

chr14: 101033755-101033836 [+]

Clustered miRNAs

17 other miRNAs are < 10 kb from hsa-mir-495

Disease association

hsa-mir-495 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-495-3p

• Accession: MIMAT0002817
• Description: Homo sapiens hsa-miR-495-3p mature miRNA
• Sequence: 50 - AAACAAACAUGGUGCACUUCUU - 71
• Evidence: experimental ; array-cloned [1], cloned [2], SOLiD [3]

Mature hsa-miR-495-5p

• Accession: MIMAT0022924
• Description: Homo sapiens hsa-miR-495-5p mature miRNA
• Sequence: 14 - GAAGUUGCCCAUGUUAUUUUCG - 35
• Evidence: experimental ; SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


3. PubMed ID: 22282338
   Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs
   "Voellenkle C, Rooij Jv, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L, David M, Capogrossi MC, Moles A, Felsani A, Martelli F"
   "RNA (2012) 18:472-484