Stem-loop hsa-mir-515-1

Accession

MI0003144

Symbol

HGNC: MIR515-1

Description

Homo sapiens hsa-mir-515-1 precursor miRNA mir-515

Gene
family

RF00639; mir-515

Literature search

36 open access papers mention hsa-mir-515-1
(67 sentences)

Sequence

96 reads, 13 reads per million, 20 experiments

ucucaugcagucaUUCUCCAAAAGAAAGCACUUUCUGuugucugaaagcaGAGUGCCUUCUUUUGGAGCGUUacuguuugaga
(((((.(((((.((.(((((((((((.((((..((((((.......)))))))))).))))))))))).)).))))).)))))

Structure

     u     c  U           A    UU      gu 
ucuca gcagu aU CUCCAAAAGAA GCAC  UCUGuu  c
||||| ||||| || ||||||||||| ||||  ||||||  u
agagu uguca UG GAGGUUUUCUU CGUG  AGacga  g
     u     U  C           C    --      aa 

Annotation confidence Low

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr19: 53679003-53679085 [+]

Clustered miRNAs

9 other miRNAs are < 10 kb from hsa-mir-515-1

Disease association

hsa-mir-515-1 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-515-5p

• Accession: MIMAT0002826
• Description: Homo sapiens hsa-miR-515-5p mature miRNA
• Sequence: 14 - UUCUCCAAAAGAAAGCACUUUCUG - 37
• Evidence: experimental ; array-cloned [1], cloned [2]

Mature hsa-miR-515-3p

• Accession: MIMAT0002827
• Description: Homo sapiens hsa-miR-515-3p mature miRNA
• Sequence: 51 - GAGUGCCUUCUUUUGGAGCGUU - 72
• Evidence: experimental ; array-cloned [1], cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770