Accession
MI0003146
Symbol
HGNC:
MIR520F
Description
Homo sapiens
hsa-mir-520f precursor miRNA mir-515
Gene
family?
family?
RF00639;
mir-515
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR520F is a miRNA gene that has been studied in various contexts. In glioblastoma patients, the levels of MIR520F, along with other miRNAs such as miR-21, miR-218, and miR-193b, were found to correlate with those detected from tissue biopsies [PMC6679205]. In hepatocellular carcinoma (HCC), the TCGA miRNA-seq dataset was used to analyze the cumulative expression of all 46 C19MC miRNA genes, including MIR520F [PMC7378193]. Furthermore, in glioblastoma patients, a panel of nine miRNAs including MIR520F was found to correlate with tissue biopsies and showed associations with tumor volume [PMC7014190] [PMC9965735]. Additionally, MIR520F was listed as part of a group of microRNAs detected in cerebrospinal fluid (CSF) samples [PMC8833415]. In breast invasive carcinoma samples, cumulative expression analysis included MIR520F among the 46 C19MC miRNA genes studied [PMC6193703]. Finally, in the context of recurrent pregnancy loss (RPL), MIR520F was found to be downregulated along with other microRNAs such as miR3175 and miR4672 [PMC5572592]. These studies highlight the involvement and potential significance of MIR520F in various diseases and biological processes.
Literature search
36 open access papers mention hsa-mir-520f
(189 sentences)
(189 sentences)
Sequence
252
reads,
22
reads per million, 8 experiments
ucucaggcugugacCCUCUAAAGGGAAGCGCUUUCUguggucagaaagaaaagcAAGUGCUUCCUUUUAGAGGGUUaccguuuggga
((((((((.((((((((((((((((((((((((((((....)))).........)))))))))))))))))))))))).))))))))
((((((((.((((((((((((((((((((((((((((....)))).........)))))))))))))))))))))))).))))))))
Structure
u --------- u
ucucaggc gugacCCUCUAAAGGGAAGCGCUU UCUg g
|||||||| |||||||||||||||||||||||| ||||
aggguuug caUUGGGAGAUUUUCCUUCGUGAA agac g
c cgaaaagaa u
Annotation confidence
Not enough data
Do you think this miRNA is real?
Genome context
chr19: 53682159-53682245 [+]
Clustered miRNAs
8 other miRNAs are < 10 kb from hsa-mir-520f
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-520f is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-520f-3p
| Accession | MIMAT0002830 |
| Description | Homo sapiens hsa-miR-520f-3p mature miRNA |
| Sequence | 55 - AAGUGCUUCCUUUUAGAGGGUU - 76 |
| Evidence |
experimental
array-cloned [1], Illumina [2] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-520f-5p
| Accession | MIMAT0026609 |
| Description | Homo sapiens hsa-miR-520f-5p mature miRNA |
| Sequence | 15 - CCUCUAAAGGGAAGCGCUUUCU - 36 |
| Evidence |
experimental
Illumina [2] |
References
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