Stem-loop hsa-mir-519d

Accession

MI0003162

Symbol

HGNC: MIR519D

Description

Homo sapiens hsa-mir-519d precursor miRNA mir-515

Gene
family

RF00639; mir-515

Literature search

42 open access papers mention hsa-mir-519d
(164 sentences)

Sequence

54 reads, 1 reads per million, 12 experiments

ucccaugcugugacCCUCCAAAGGGAAGCGCUUUCUGUUuguuuucucuuaaaCAAAGUGCCUCCCUUUAGAGUGuuaccguuuggga
(((((.((.(((((.(((.(((((((.((((((..((((((........)))))))))))).))))))).))).))))).)).)))))

Structure

     u  u     C   C       A      UC      uuu 
uccca gc gugac CUC AAAGGGA GCGCUU  UGUUug   u
||||| || ||||| ||| ||||||| ||||||  ||||||    
agggu ug cauuG GAG UUUCCCU CGUGAA  ACaaau   c
     u  c     U   A       C      --      ucu 

Annotation confidence Not enough data

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr19: 53713347-53713434 [+]

Clustered miRNAs

9 other miRNAs are < 10 kb from hsa-mir-519d

Disease association

hsa-mir-519d is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-519d-3p

• Accession: MIMAT0002853
• Description: Homo sapiens hsa-miR-519d-3p mature miRNA
• Sequence: 54 - CAAAGUGCCUCCCUUUAGAGUG - 75
• Evidence: experimental ; array-cloned [1], cloned [2], Illumina [3]

Mature hsa-miR-519d-5p

• Accession: MIMAT0026610
• Description: Homo sapiens hsa-miR-519d-5p mature miRNA
• Sequence: 15 - CCUCCAAAGGGAAGCGCUUUCUGUU - 39
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45