Stem-loop hsa-mir-510

Accession

MI0003197

Symbol

HGNC: MIR510

Description

Homo sapiens hsa-mir-510 precursor miRNA mir-509

Gene
family

RF04216; mir-509

Literature search

15 open access papers mention hsa-mir-510
(144 sentences)

Sequence

1421 reads, 31 reads per million, 25 experiments

gugguguccUACUCAGGAGAGUGGCAAUCACauguaauuaggugugAUUGAAACCUCUAAGAGUGGAguaacac
(((...(((.((((.((((.((..(((((((((........)))))))))..))))))..)))))))....)))

Structure

   -gug   U    -A    A  GG         gua 
gug    ucc ACUC  GGAG GU  CAAUCACau   a
|||    ||| ||||  |||| ||  |||||||||    
cac    AGG UGAG  UCUC CA  GUUAgugug   u
   aaug   -    AA    -  AA         gau 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chrX: 147272335-147272408 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from hsa-mir-510

Disease association

hsa-mir-510 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-510-5p

• Accession: MIMAT0002882
• Description: Homo sapiens hsa-miR-510-5p mature miRNA
• Sequence: 10 - UACUCAGGAGAGUGGCAAUCAC - 31
• Evidence: experimental ; array-cloned [1], cloned [2], Illumina [3]

Mature hsa-miR-510-3p

• Accession: MIMAT0026613
• Description: Homo sapiens hsa-miR-510-3p mature miRNA
• Sequence: 47 - AUUGAAACCUCUAAGAGUGGA - 67
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45