miRBase entry: hsa-mir-550a-1

Stem-loop hsa-mir-550a-1


Accession
MI0003600
Symbol
HGNC: MIR550A1
Description
Homo sapiens hsa-mir-550a-1 precursor miRNA mir-550
Gene
family?
RF00873; mir-550

Literature search
18 open access papers mention hsa-mir-550a-1
(116 sentences)

Sequence

7336 reads, 232 reads per million, 123 experiments
ugaugcuuugcuggcuggugcAGUGCCUGAGGGAGUAAGAGCCCuguuguuguaagauagUGUCUUACUCCCUCAGGCACAUcuccaacaagucucu
.((.((((.(.(((..(((...((((((((((((((((((.(.(((((.......))))).)))))))))))))))))))))).))).))))).)).

Structure
u  u    u c   cu   gcA                  G C     gu 
 ga gcuu g ugg  ggu   GUGCCUGAGGGAGUAAGA C Cuguu  u
 || |||| | |||  |||   |||||||||||||||||| | |||||  g
 cu ugaa c acc  cUA   CACGGACUCCCUCAUUCU G gauag  u
u  c    - a   -u   ---                  - U     aa 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chr7: 30289794-30289890 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-550a-1
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-550a-1 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-550a-5p

Accession MIMAT0004800
Description Homo sapiens hsa-miR-550a-5p mature miRNA
Sequence 22 - AGUGCCUGAGGGAGUAAGAGCCC - 44
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-550a-3p

Accession MIMAT0003257
Description Homo sapiens hsa-miR-550a-3p mature miRNA
Sequence 61 - UGUCUUACUCCCUCAGGCACAU - 82
Evidence experimental
RAKE [1], Illumina [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16505370
    The colorectal microRNAome
    "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
    "Proc Natl Acad Sci U S A (2006) 103:3687-3692