Stem-loop hsa-mir-590

Accession

MI0003602

Symbol

HGNC: MIR590

Description

Homo sapiens hsa-mir-590 precursor miRNA mir-590

Gene
family

RF00928; mir-590

Literature search

68 open access papers mention hsa-mir-590
(418 sentences)

Sequence

92304 reads, 292 reads per million, 152 experiments

uagccagucagaaauGAGCUUAUUCAUAAAAGUGCAGuauggugaagucaaucugUAAUUUUAUGUAUAAGCUAGUcucugauugaaacaugcagca
....((((((((.((.(((((((.(((((((.(((((..(((.....)))..))))).))))))).))))))).)).))))))))............

Structure

--------uagc        a  G       U       G     ua   u 
            cagucaga au AGCUUAU CAUAAAA UGCAG  ugg g
            |||||||| || ||||||| ||||||| |||||  ||| a
            guuagucu UG UCGAAUA GUAUUUU AUguc  acu a
acgacguacaaa        c  A       U       A     ua   g 

Annotation confidence High

Genome context

chr7: 74191198-74191294 [+]

Disease association

hsa-mir-590 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-590-5p

• Accession: MIMAT0003258
• Description: Homo sapiens hsa-miR-590-5p mature miRNA
• Sequence: 16 - GAGCUUAUUCAUAAAAGUGCAG - 37
• Evidence: experimental ; Microarray [1], SAGE [1], cloned [2]

Mature hsa-miR-590-3p

• Accession: MIMAT0004801
• Description: Homo sapiens hsa-miR-590-3p mature miRNA
• Sequence: 56 - UAAUUUUAUGUAUAAGCUAGU - 76
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692