Accession
MI0003678
Symbol
HGNC:
MIR656
Description
Homo sapiens
hsa-mir-656 precursor miRNA
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR656 is a microRNA that has been implicated in various biological processes and diseases. It has been found to be associated with sensitivity to KIN001-236 in ovarian cell lines and bleomycin in renal cell carcinoma cell lines [PMC9716673]. Additionally, MIR656 has been identified as a potential gene associated with the progression of severe pneumonia [PMC6090384]. It is worth noting that MIR656, along with EIF5AP4, are novel genes that have not yet been reported to be related to pneumonia [PMC6090384]. MIR656 has also been identified as a gene that shows a significantly lower methylation rate in invasive adenocarcinoma relative to AIS [PMC6422190]. In the context of multiple sclerosis, MIR656 is one of the miRNAs that seem to be less expressed in the diseased context [PMC4655260]. Furthermore, MIR656 has shown decreased expression levels in certain brain regions compared to others [PMC7848201]. Overall, these findings suggest that MIR656 may play important roles in various biological processes and diseases.
Literature search
12 open access papers mention hsa-mir-656
(38 sentences)
(38 sentences)
Sequence
377
reads,
21
reads per million, 62 experiments
cugaaauAGGUUGCCUGUGAGGUGUUCAcuuucuauaugaugAAUAUUAUACAGUCAACCUCUuuccgauaucgaauc
..((((.((((((.(((((.((((((((...((.....)))))))))).))))).)))))).))))............
..((((.((((((.(((((.((((((((...((.....)))))))))).))))).)))))).))))............
Structure
----------cu u C A cuu u
gaaa AGGUUG CUGUG GGUGUUCA uc a
|||| |||||| ||||| |||||||| || u
cuuU UCCAAC GACAU UUAUAAgu ag a
cuaagcuauagc C U A --- u
Annotation confidence
High
Do you think this miRNA is real?
Genome context
chr14: 101066724-101066801 [+]
Clustered miRNAs
8 other miRNAs are < 10 kb from hsa-mir-656
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-656 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-656-3p
| Accession | MIMAT0003332 |
| Description | Homo sapiens hsa-miR-656-3p mature miRNA |
| Sequence | 43 - AAUAUUAUACAGUCAACCUCU - 63 |
| Evidence |
experimental
Microarray [1], RT-PCR [1], SAGE [1], Illumina [2] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-656-5p
| Accession | MIMAT0026627 |
| Description | Homo sapiens hsa-miR-656-5p mature miRNA |
| Sequence | 8 - AGGUUGCCUGUGAGGUGUUCA - 28 |
| Evidence |
experimental
Illumina [2] |
References
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