Stem-loop hsa-mir-759

Accession

MI0004065

Symbol

HGNC: MIR759

Description

Homo sapiens hsa-mir-759 precursor miRNA

Sequence

uaauaaauuaaaugccuaaacugGCAGAGUGCAAACAAUUUUGACucagaucuaaauguuugcacuggcuguuuaaacauuuaauuuguua
((((((((((((((..(((((.(((..((((((((((.(((.((......)).))))))))))))).))))))))..))))))))))))))

Structure

              cc     u   AG          A   U  Cu 
uaauaaauuaaaug  uaaac gGC  AGUGCAAACA UUU GA  c
||||||||||||||  ||||| |||  |||||||||| ||| ||   
auuguuuaauuuac  auuug ucg  ucacguuugu aaa cu  a
              aa     -   -g          -   u  ag 

Annotation confidence Not enough data

Comments

Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method [1]. Artzi et al. later showed that it is a homolog of a validated miRNA in mouse [2].

Genome context

chr13: 52810050-52810140 [+]

Disease association

hsa-mir-759 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-759

• Accession: MIMAT0010497
• Description: Homo sapiens hsa-miR-759 mature miRNA
• Sequence: 24 - GCAGAGUGCAAACAAUUUUGAC - 45
• Evidence: experimental ; RAKE [1]

References

1. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298


2. PubMed ID: 18215311
   miRNAminer: a tool for homologous microRNA gene search
   "Artzi S, Kiezun A, Shomron N"
   "BMC Bioinformatics (2008) 9:39