miRBase entry: mmu-mir-421

Stem-loop mmu-mir-421


Accession
MI0005496
Symbol
MGI: Mir421
Description
Mus musculus mmu-mir-421 precursor miRNA mir-95
Gene
family?
RF04053; mir-95

Literature search
19 open access papers mention mmu-mir-421
(43 sentences)

Sequence

17237 reads, 144 reads per million, 100 experiments
cauuguaggcCUCAUUAAAUGUUUGUUGAAUgaaaaaaugaaucAUCAACAGACAUUAAUUGGGCGCcugcucugu
((..((((((((((...((((((((((((.(((.........)))))))))))))))...)))).))))))..)).

Structure
-  uu      -    UUA            A   aaa 
 ca  guaggc CUCA   AAUGUUUGUUGA Uga   a
 ||  |||||| ||||   |||||||||||| |||   a
 gu  cgucCG GGGU   UUACAGACAACU Acu   u
u  cu      C    UAA            -   aag 


Annotation confidence High
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Genome context
chrX: 103572921-103572996 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from mmu-mir-421
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-421-5p

Accession MIMAT0017273
Description Mus musculus mmu-miR-421-5p mature miRNA
Sequence 11 - CUCAUUAAAUGUUUGUUGAAU - 31
Evidence experimental
Illumina [3]
Database links
Predicted targets

Mature mmu-miR-421-3p

Accession MIMAT0004869
Description Mus musculus mmu-miR-421-3p mature miRNA
Sequence 45 - AUCAACAGACAUUAAUUGGGCGC - 67
Evidence experimental
cloned [1], Illumina [2-3]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  3. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009