miRBase entry: hsa-mir-450b

Stem-loop hsa-mir-450b

Accession

MI0005531

Symbol

HGNC: MIR450B

Description

Homo sapiens hsa-mir-450b precursor miRNA mir-450

Gene
family?

RF00708; mir-450

Literature search

24 open access papers mention hsa-mir-450b
(40 sentences)

Sequence

7019 reads, 50 reads per million, 92 experiments

gcagaauuauUUUUGCAAUAUGUUCCUGAAUAuguaauauaaguguaUUGGGAUCAUUUUGCAUCCAUAguuuuguau
((((((((((...(((((.(((.((((((((((.........)))).)))))).))).)))))...))))))))))..

Structure

--          UUU     U   U      -    gua 
  gcagaauuau   UGCAA AUG UCCUGA AUAu   a
  ||||||||||   ||||| ||| |||||| ||||   u
  uguuuugAUA   ACGUU UAC AGGGUU ugug   a
ua          CCU     U   U      a    aau

Annotation confidence High

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Genome context

chrX: 134540185-134540262 [-]

Clustered miRNAs

5 other miRNAs are < 10 kb from hsa-mir-450b

Name	Accession	Chromosome	Start	End	Strand	Confidence

Disease association

hsa-mir-450b is associated with one or more human diseases in the Human microRNA Disease Database

Disease	Description	Category	PubMed ID

Database links

Mature hsa-miR-450b-5p

Accession	MIMAT0004909
Description	Homo sapiens hsa-miR-450b-5p mature miRNA
Sequence	11 - UUUUGCAAUAUGUUCCUGAAUA - 32
Evidence	experimental cloned [1]
Database links
Predicted targets

Mature hsa-miR-450b-3p

Accession	MIMAT0004910
Description	Homo sapiens hsa-miR-450b-3p mature miRNA
Sequence	48 - UUGGGAUCAUUUUGCAUCCAUA - 69
Evidence	experimental cloned [1]
Database links
Predicted targets

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414