Stem-loop hsa-mir-873

Accession

MI0005564

Symbol

HGNC: MIR873

Description

Homo sapiens hsa-mir-873 precursor miRNA mir-873

Gene
family

RF00910; mir-873

Literature search

19 open access papers mention hsa-mir-873
(34 sentences)

Sequence

4220 reads, 33 reads per million, 75 experiments

gugugcauuuGCAGGAACUUGUGAGUCUCCUauugaaaaugaacaGGAGACUGAUGAGUUCCCGGGAacacccacaa
(((.(..(((.(.(((((((((.((((((((.((.......)).)))))))).))))))))).).)))..).)))..

Structure

--   u ca   G A         G        a  ga 
  gug g  uuu C GGAACUUGU AGUCUCCU uu  a
  ||| |  ||| | ||||||||| |||||||| ||  a
  cac c  aAG G CCUUGAGUA UCAGAGGa aa  a
aa   c ac   G C         G        c  gu 

Annotation confidence High

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

chr9: 28888879-28888955 [-]

Disease association

hsa-mir-873 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-873-5p

• Accession: MIMAT0004953
• Description: Homo sapiens hsa-miR-873-5p mature miRNA
• Sequence: 11 - GCAGGAACUUGUGAGUCUCCU - 31
• Evidence: experimental ; cloned [2]

Mature hsa-miR-873-3p

• Accession: MIMAT0022717
• Description: Homo sapiens hsa-miR-873-3p mature miRNA
• Sequence: 46 - GGAGACUGAUGAGUUCCCGGGA - 67
• Evidence: not_experimental

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298