Stem-loop mmu-mir-1983

Accession

MI0009990

Symbol

MGI: Mir1983

Description

Mus musculus mmu-mir-1983 precursor miRNA

Literature search

17 open access papers mention mmu-mir-1983
(32 sentences)

Sequence

50810 reads, 156.0 reads per million, 160 experiments

ccuuuacagagaaagcauGCUCCAGUGGCGCAAUCGGUuagcgcgcgguacuuauacagcaguauaugugcgggugaugccgagguugugaguucgagcCUCACCUGGAGCAUGUUUUCUucccuuuccgcc
........(((((((((((((((((..((((.........)))).(.((((.(((((....))))).)))).)((((.((((((........)))).)).)))))))))))))))))))))...........

Structure

---ccuuuaca                 ----------------------------------------------------------UG    AAU 
           gagaaagcauGCUCCAG                                                            GCGC   C
           |||||||||||||||||                                                            ||||   G
           uUCUUUUGUACGAGGUC                                                            cgcg   G
ccgccuuuccc                 CACUCcgagcuugaguguuggagccguagugggcguguauaugacgacauauucauggcg    auU 

Annotation confidence Medium

Comments

Babiarz et al. show that mir-1983 is derived from Dicer-dependent processing of an alternative hairpin conformation of a tRNA(Ile) sequence [1]. The biological significance of the mature miRNA is unknown, and tRNA-derived miRNA sequences are not expected to be prevalent.

Genome context

13: 22081088-22081219 [-]

Mature mmu-miR-1983-5p

• Accession: MIMAT0050719
• Description: Mus musculus mmu-miR-1983-5p mature miRNA
• Sequence: 19 - GCUCCAGUGGCGCAAUCGGU - 38
• Evidence: experimental ; Illumina [1]

Mature mmu-miR-1983-3p

• Accession: MIMAT0009455
• Description: Mus musculus mmu-miR-1983-3p mature miRNA
• Sequence: 100 - CUCACCUGGAGCAUGUUUUCU - 120
• Evidence: experimental ; Illumina [1]

References

1. PubMed ID: 18923076
   Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs
   "Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R"
   "Genes Dev (2008) 22:2773-2785