Stem-loop bma-mir-2d

Accession

MI0026298

Description

Brugia malayi bma-mir-2d precursor miRNA

Literature search

3 open access papers mention bma-mir-2d
(32 sentences)

Sequence

29177 reads, 1713.0 reads per million, 21 experiments

uucugaaagugcaaguaacagcCGUUGUAUCAUUUGUGAUUUAUGuuuuauuaucgcuuaucaUAUCACAGAAUUGAUGCAGCGAGCuguacuugucgcaauauucagaa
.((((((.(((((((((.(((((((((((((((((((((..((((................)))))))))))..)))))))))).)))))))))).)))....)))))).

Structure

u      ---a   -      a    -          --       UU    uuuuauu 
 ucugaa    gug caagua cagc CGUUGUAUCA  UUUGUGA  UAUG       a
 ||||||    ||| |||||| |||| ||||||||||  |||||||  ||||        
 agacuu    cgc guucau guCG GCGACGUAGU  AGACACU  AUac       u
a      auaa   u      -    A          UA       --    uauucgc 

Annotation confidence High

Comments

This microRNA was experimentally validated from deep sequencing libraries in the closely related species Brugia pahangi [1].

Genome context

Bmal_v3_scaffold153: 15939-16048 [+]

Clustered miRNAs

9 other miRNAs are < 10 kb from bma-mir-2d

Mature bma-miR-2d-5p

• Accession: MIMAT0057244
• Description: Brugia malayi bma-miR-2d-5p mature miRNA
• Sequence: 23 - CGUUGUAUCAUUUGUGAUUUAUG - 45
• Evidence: experimental ; Illumina [2]

Mature bma-miR-2d-3p

• Accession: MIMAT0031747
• Description: Brugia malayi bma-miR-2d-3p mature miRNA
• Sequence: 64 - UAUCACAGAAUUGAUGCAGCGAGC - 87
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 22216965
   Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel
   Winter AD, Weir W, Hunt M, Berriman M, Gilleard JS, Devaney E, Britton C
   BMC Genomics (2012) 13:4


2. PubMed ID: 24824352
   Diversity and expression of microRNAs in the filarial parasite, Brugia malayi
   Poole CB, Gu W, Kumar S, Jin J, Davis PJ, Bauche D, McReynolds LA
   PLoS One (2014) 9:e96498