miRBase entry: mml-mir-181a-1

Stem-loop mml-mir-181a-1


Accession
MI0002931
Description
Macaca mulatta mml-mir-181a-1 precursor miRNA
Gene family
MIPF0000007; mir-181

Literature search
3 open access papers mention mml-mir-181a-1
(45 sentences)

Sequence

2022539 reads, 12814 reads per million, 9 experiments
ugaguuuugagguugcuucagugAACAUUCAACGCUGUCGGUGAGUuuggaauuaaaaucaaaACCAUCGACCGUUGAUUGUACCcuauggcuaaccaucaucuacucca
.((((..((((((((((..((.(.(((.((((((..(((((((.((((.((.......)).))))))))))))))))).))).).))..))).)))).)))...))))..

Structure
-u    -uu   -    -   uc  u A   U      CU       A    g  au 
  gagu   uga gguu gcu  ag g ACA UCAACG  GUCGGUG GUuu ga  u
  ||||   ||| |||| |||  || | ||| ||||||  ||||||| |||| ||  a
  cuca   acu ccaa cgg  uc C UGU AGUUGC  CAGCUAC CAaa cu  a
ac    ucu   a    u   ua  C A   U      --       -    a  aa 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context
chr1: 167910267-167910376 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from mml-mir-181a-1
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mml-miR-181a-5p

Accession MIMAT0002506
Description Macaca mulatta mml-miR-181a-5p mature miRNA
Sequence 24 - AACAUUCAACGCUGUCGGUGAGU - 46
Evidence not_experimental
Database links
Predicted targets

Mature mml-miR-181a-3p

Accession MIMAT0002622
Description Macaca mulatta mml-miR-181a-3p mature miRNA
Sequence 64 - ACCAUCGACCGUUGAUUGUACC - 85
Evidence not_experimental
Database links
Predicted targets

References

  1. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24