Stem-loop sequence mmu-mir-487b

Accession

MI0003534

Symbol

MGI:Mir487b

Description

Mus musculus miR-487b stem-loop

Gene family

MIPF0000018; mir-154

Stem-loop

u      ug        uuau      c uc    - uuc 
 gguacu  gagagugg    cccugu c  uucg c   a
 ||||||  ||||||||    |||||| |  |||| |   c
 cuauga  uuuucacc    gggaca g  aagc g   u
a      cu        uacu      u cu    c uac 

Deep sequencing

25782 reads, 55 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38): chr12: 109727333-109727414 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-487b

• mmu-mir-495: chr12: 109718754-109718816 [+]
• mmu-mir-667: chr12: 109720006-109720097 [+]
• mmu-mir-376c: chr12: 109722718-109722803 [+]
• mmu-mir-654: chr12: 109723218-109723301 [+]
• mmu-mir-376b: chr12: 109723458-109723539 [+]
• mmu-mir-376a: chr12: 109723781-109723848 [+]
• mmu-mir-300: chr12: 109724313-109724391 [+]
• mmu-mir-381: chr12: 109726822-109726896 [+]
• mmu-mir-487b: chr12: 109727333-109727414 [+]
• mmu-mir-539: chr12: 109728129-109728202 [+]
• mmu-mir-544: chr12: 109729325-109729402 [+]
• mmu-mir-382: chr12: 109733771-109733846 [+]
• mmu-mir-134: chr12: 109734139-109734209 [+]
• mmu-mir-668: chr12: 109734732-109734797 [+]
• mmu-mir-485: chr12: 109734902-109734974 [+]
• mmu-mir-453: chr12: 109735619-109735700 [+]

Database links

• ENTREZGENE: 723940;Mir487b
• MGI: 3619424;Mir487b

Mature sequence mmu-miR-487b-5p

• Accession: MIMAT0017216
• Previous IDs: mmu-miR-487b*
• Sequence: 15 - ugguuaucccuguccucuucg - 35
• Deep sequencing: 73 reads, 16 experiments
• Evidence: experimental; Solexa [4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-487b-5p
  • MIRDB:mmu-miR-487b-5p
  • RNA22-MMU:mmu-miR-487b-5p

Mature sequence mmu-miR-487b-3p

• Accession: MIMAT0003184
• Previous IDs: mmu-miR-487b
• Sequence: 50 - aaucguacagggucauccacuu - 71
• Deep sequencing: 25693 reads, 53 experiments
• Evidence: experimental; cloned [1-2], Solexa [3-4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-487b-3p
  • MICRORNA.ORG:mmu-miR-487b-3p
  • MIRDB:mmu-miR-487b-3p
  • RNA22-MMU:mmu-miR-487b-3p
  • TARGETSCAN-VERT:mmu-miR-487b

References

1. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).