miRBase entry: mdv1-mir-M4

Stem-loop mdv1-mir-M4


Accession
MI0005096
Description
Mareks disease virus type 1 mdv1-mir-M4 precursor miRNA


Sequence

gaaguUUAAUGCUGUAUCGGAACCCUUCguucggugaccacgAAUGGUUCUGACAGCAUGACCuuu
((((....((((((..((((((((.(((((..((...))))))).))))))))))))))...))))

Structure
    uUUA      UA        C     uc  u 
gaag    AUGCUG  UCGGAACC UUCgu  gg  
||||    ||||||  |||||||| |||||  || g
uuuC    UACGAC  AGUCUUGG AAgca  cc  
    -CAG      --        U     --  a 


Annotation confidence Not enough data
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Genome context
AF243438.1: 7192-7257 [-]
Clustered miRNAs
8 other miRNAs are < 10 kb from mdv1-mir-M4
Name Accession Chromosome Start End Strand Confidence




Disease association
mdv1-mir-M4 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature mdv1-miR-M4-5p

Accession MIMAT0003924
Description Mareks disease virus type 1 mdv1-miR-M4-5p mature miRNA
Sequence 6 - UUAAUGCUGUAUCGGAACCCUUC - 28
Evidence experimental
cloned [1-3], Northern [1-2], Illumina [4]

Mature mdv1-miR-M4-3p

Accession MIMAT0003925
Description Mareks disease virus type 1 mdv1-miR-M4-3p mature miRNA
Sequence 43 - AAUGGUUCUGACAGCAUGACC - 63
Evidence experimental
cloned [1-3], Northern [1-2], Illumina [4]

References

  1. PubMed ID: 18256158
    MicroRNA profile of Marek's disease virus-transformed T-cell line MSB-1: predominance of virus-encoded microRNAs
    "Yao Y, Zhao Y, Xu H, Smith LP, Lawrie CH, Watson M, Nair V"
    "J Virol (2008) 82:4007-4015

  2. PubMed ID: 16912324
    Marek's disease virus encodes MicroRNAs that map to meq and the latency-associated transcript
    "Burnside J, Bernberg E, Anderson A, Lu C, Meyers BC, Green PJ, Jain N, Isaacs G, Morgan RW"
    "J Virol (2006) 80:8778-8786

  3. PubMed ID: 18430245
    Deep sequencing of chicken microRNAs
    Burnside J, Ouyang M, Anderson A, Bernberg E, Lu C, Meyers BC, Green PJ, Markis M, Isaacs G, Huang E, Morgan RW
    BMC Genomics (2008) 9:185

  4. PubMed ID: 18842708
    Sequence conservation and differential expression of Marek's disease virus microRNAs
    "Morgan R, Anderson A, Bernberg E, Kamboj S, Huang E, Lagasse G, Isaacs G, Parcells M, Meyers BC, Green PJ, Burnside J"
    "J Virol (2008) 82:12213-12220