miRBase entry: hsv1-mir-H5

Stem-loop hsv1-mir-H5


Accession
MI0008940
Description
Herpes Simplex Virus 1 hsv1-mir-H5 precursor miRNA
Gene family
MIPF0000966; mir-H5


Sequence

gcgcucccucGGGGGGGUUCGGGCAUCUCUACcucagugccgccaaucucagGUCAGAGAUCCAAACCCUCCGGgggcgc
((((((((...((((((((..((.((((((((((.((..........)).)))).)))))))).))))))))))))))))

Structure
        ucG        CG  C      -    c  ugcc 
gcgcuccc   GGGGGGUU  GG AUCUCU ACcu ag    g
||||||||   ||||||||  || |||||| |||| ||     
cgcgggGG   CCUCCCAA  CC UAGAGA UGga uc    c
        ---        -A  -      C    c  uaac 


Annotation confidence Not enough data
Do you think this miRNA is real?

Genome context
Unknown

Database links

Mature hsv1-miR-H5-5p

Accession MIMAT0015280
Description Herpes Simplex Virus 1 hsv1-miR-H5-5p mature miRNA
Sequence 11 - GGGGGGGUUCGGGCAUCUCUAC - 32
Evidence experimental
Illumina [3]

Mature hsv1-miR-H5-3p

Accession MIMAT0008403
Description Herpes Simplex Virus 1 hsv1-miR-H5-3p mature miRNA
Sequence 53 - GUCAGAGAUCCAAACCCUCCGG - 74
Evidence experimental
454 [1], qRT-PCR [1], Illumina [2-3]

References

  1. PubMed ID: 20181707
    Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2
    "Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM"
    "J Virol (2010) 84:4659-4672

  2. PubMed ID: 18596690
    MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs
    "Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR"
    "Nature (2008) 454:780-783

  3. PubMed ID: 19656888
    Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia
    "Umbach JL, Nagel MA, Cohrs RJ, Gilden DH, Cullen BR"
    "J Virol (2009) 83:10677-10683