Stem-loop aae-mir-281

Accession

MI0013447

Description

Aedes aegypti aae-mir-281 precursor miRNA

Gene family

MIPF0000087; mir-46

Literature search

5 open access papers mention aae-mir-281
(10 sentences)

Sequence

27115 reads, 1377 reads per million, 2 experiments

ugguuucgaauaugaaaauaAAGAGAGCUAUCCGUCGACaguagggauaugauucacUGUCAUGGAAUUGCUCUCUUUAuguacaauucgauauuca
.(((.((((((.((...(((((((((((..(((((.((((((.((........)))))))))))))...)))))))))))...)))))))).)))..

Structure

-u   u      a  aaa           -UA     C      a  gau 
  ggu ucgaau ug   auaAAGAGAGC   UCCGU GACagu gg   a
  ||| |||||| ||   |||||||||||   ||||| |||||| ||    
  uua agcuua ac   uAUUUCUCUCG   AGGUA CUGUca cu   u
ac   u      -  aug           UUA     -      -  uag 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.957: 134442-134538 [+]

Mature aae-miR-281-5p

• Accession: MIMAT0014231
• Description: Aedes aegypti aae-miR-281-5p mature miRNA
• Sequence: 21 - AAGAGAGCUAUCCGUCGAC - 39
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-281-3p

• Accession: MIMAT0014232
• Description: Aedes aegypti aae-miR-281-3p mature miRNA
• Sequence: 58 - UGUCAUGGAAUUGCUCUCUUUA - 79
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119