miRBase entry: aae-mir-1889

Stem-loop aae-mir-1889


Accession
MI0013448
Description
Aedes aegypti aae-mir-1889 precursor miRNA
Gene family
MIPF0000954; mir-1889

Literature search
3 open access papers mention aae-mir-1889
(18 sentences)

Sequence

2728 reads, 141 reads per million, 2 experiments
gaggUAAUCUCAAAUUGUAACAGUGGguugauuuuccuggugaaucccggccuuguccuccgucacaagugugacaagugucucgaaaacguguucgcuauaccCACGUUACAGAUUGGGGUUUCCcc
..((.((((((((.(((((((.((((((.(((....((((......))))....)))....(((((....))))).((((.(.((....)).)..))))..))))))))))))).)))))))).))..

Structure
ga  U        A       A      -------------------------------------------u   uuuc    ug 
  gg AAUCUCAA UUGUAAC GUGGgu                                            gau    cugg  a
  || |||||||| ||||||| ||||||                                            |||    ||||   
  CC UUGGGGUU GACAUUG CACcca                                            cug    ggcc  a
cc  U        A       -      uaucgcuugugcaaaagcucugugaacagugugaacacugccuc   uucc    cu 


Annotation confidence High
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Comments
This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context
supercont1.68: 2720794-2720921 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from aae-mir-1889
Name Accession Chromosome Start End Strand Confidence




Database links

Mature aae-miR-1889-5p

Accession MIMAT0014233
Description Aedes aegypti aae-miR-1889-5p mature miRNA
Sequence 5 - UAAUCUCAAAUUGUAACAGUGG - 26
Evidence experimental
Illumina [2]

Mature aae-miR-1889-3p

Accession MIMAT0014234
Description Aedes aegypti aae-miR-1889-3p mature miRNA
Sequence 105 - CACGUUACAGAUUGGGGUUUCC - 126
Evidence experimental
454 [1], Illumina [2]

References

  1. PubMed ID: 19961592
    Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
    Li S, Mead EA, Liang S, Tu Z
    BMC Genomics (2009) 10:581

  2. PubMed ID: 20167119
    Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
    Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
    BMC Genomics (2010) 11:119