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28 publications mentioning ssc-mir-29b-2

Open access articles that are associated with the species Sus scrofa and mention the gene name mir-29b-2. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 37
This concurs with the expression of the apoptosis-related genes, all down-regulated at day 3 compared to their initial up-regulation on day 1. The same pattern holds true for the expression IFIH1 and TLR3 and the miRNAs that target them (ssc-miR-29b, ssc-miR-18a, and hsa-miR-590-3p). [score:12]
Common to all five miRNAs found to correlate negatively with apoptosis-related gene expression (ssc-miR-15a, ssc-miR-18a, ssc-miR-21, ssc-miR-29b, and hsa-miR-590-3p) is that they were significantly up-regulated on day 3 after challenge, and not regulated at other time points. [score:7]
Finally, we also found ssc-miR-29b to be modestly up-regulated on day 1 and 3 after challenge, suggesting that ssc-miR-29b mediated up-regulation of IL28B via COX2 and IRF7 may also contribute to the antiviral response in IAV infection in our pig mo del. [score:7]
They furthermore demonstrated that hsa-miR-29 (especially hsa-miR-29b-3p) indirectly mediate IFNL1 up-regulation by controlling DNA methyltransferase (DNMT3A and DNMT3B) activity in human pulmonary epithelial cells (A549) and a subsequent IRF3/IRF7 dependent transcription of IFNL1 via COX2 (PTGS2), a potent inflammatory protein in IAV infection [69]. [score:5]
This negative correlation between miRNA expression and their target transcripts thus suggest the specific involvement of ssc-miR-15a, ssc-miR-18a, ssc-miR-21, ssc-miR-29b, and hsa-miR-590-3p in the modulation of important signaling cascades of apoptosis and viral recognition. [score:5]
In addition to the abovementioned possible involvement of ssc-miR-29b in the IFN-λ3 response, our results likewise suggested miRNA -mediated modulation of other branches of the innate response to IAV infection in the pig. [score:1]
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2
[+] score: 32
In our study, CASP3 was significantly upregulated by qRT-PCR analysis (Figure 6) and targeted by the downregulated miRNAs: miR-342-3p, miR-29b, miR-29c, miR-29a, let-7g and miR-30b, which can be expected to develop miRNA -based therapeutics for influenza disease. [score:11]
Therefore, the downregulated miR-29 may regulate the T helper 1 (Th1) cell differentiation to secrete more IFN-gamma and mediate elimination of intracellular pathogens, but dysregulated T cell responses may also contribute to pathologic inflammation. [score:6]
MiR-29a and miR-29b were reported to be downregulated in lung tissues from mice infected with reconstructed 1918 or a nonlethal seasonal influenza virus, Tx/91 [17]. [score:4]
Both miR-29a and miR-29b could repress IFN-gamma production by direct targeting of both T-box transcription factor T-bet and Eomesodermin (Eomes), two transcription factors known to induce IFN-gamma production [63]. [score:4]
The expression of hsa-miR-150, hsa-miR-31, hsa-miR-155, hsa-miR-29a, hsa-miR-29b, hsa-miR-342-5p, and hsa-miR-146b-5p were present in lower abundance, whereas hsa-miR-148a and hsa-miR-886-3p were present in higher abundance in PBMCs from critically ill patients infected with H1N1 influenza virus than that from healthy controls. [score:3]
validation of differentially expressed miRNAs and ROC analysisThe microarray data were validated by performing, qRT-PCR for nine miRNAs, including hsa-miR-146b-5p, hsa-miR-148a, hsa-miR-150, hsa-miR-31, hsa-miR-155, hsa-miR-29a, hsa-miR-29b, hsa-miR-342-5p, and hsa-miR-886-3p. [score:3]
The microarray data were validated by performing, qRT-PCR for nine miRNAs, including hsa-miR-146b-5p, hsa-miR-148a, hsa-miR-150, hsa-miR-31, hsa-miR-155, hsa-miR-29a, hsa-miR-29b, hsa-miR-342-5p, and hsa-miR-886-3p. [score:1]
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3
[+] score: 24
The down-regulated miR-29b and miR-29a are both or each connected to up-regulated SMARCE1, HBO1, NKX6-1, HOXA10, HBP1, OTUD4, that could be further considered as potent targets during infection. [score:8]
Five miRNAs were nodal and were either up-regulated (miR-194 and miR-let7b) or down-regulated (miR-27B, miR29-a and miR29-b1). [score:7]
In particular, human EIF2C1 mRNA is a predicted target of two human miRNAs (miR-let7b and miR29b) and EIF2C4 mRNA is a predicted target of human miR-let7b [29]. [score:5]
EIF2C1 and EIF2C4 were respectively connected to miR29b and miR-27b, both down-regulated. [score:4]
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4
[+] score: 18
Other miRNAs from this paper: ssc-mir-122, ssc-mir-125b-2, ssc-mir-181b-2, ssc-mir-20a, ssc-mir-23a, ssc-mir-26a, ssc-mir-29b-1, ssc-mir-181c, ssc-mir-214, ssc-let-7c, ssc-let-7f-1, ssc-let-7i, ssc-mir-103-1, ssc-mir-107, ssc-mir-21, ssc-mir-29c, ssc-mir-30c-2, bta-mir-26a-2, bta-mir-29a, bta-let-7f-2, bta-mir-103-1, bta-mir-20a, bta-mir-21, bta-mir-26b, bta-mir-30d, bta-mir-499, bta-mir-99a, bta-mir-125b-1, bta-mir-126, bta-mir-181a-2, bta-mir-199a-1, bta-mir-30b, bta-mir-107, bta-mir-10a, bta-mir-127, bta-mir-142, bta-mir-181b-2, bta-mir-30e, bta-mir-92a-2, bta-let-7d, bta-mir-132, bta-mir-138-2, bta-mir-17, bta-mir-181c, bta-mir-192, bta-mir-199b, bta-mir-200a, bta-mir-200c, bta-mir-214, bta-mir-23a, bta-mir-29b-2, bta-mir-29c, bta-mir-455, bta-let-7g, bta-mir-10b, bta-mir-30a, bta-mir-200b, bta-let-7a-1, bta-let-7f-1, bta-mir-122, bta-mir-30c, bta-let-7i, bta-mir-25, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-103-2, bta-mir-125b-2, bta-mir-99b, ssc-mir-99b, ssc-mir-17, ssc-mir-30b, ssc-mir-199b, bta-mir-1-2, bta-mir-1-1, bta-mir-129-1, bta-mir-129-2, bta-mir-133a-2, bta-mir-133a-1, bta-mir-133b, bta-mir-135b, bta-mir-138-1, bta-mir-143, bta-mir-144, bta-mir-146b, bta-mir-146a, bta-mir-181d, bta-mir-190a, bta-mir-199a-2, bta-mir-202, bta-mir-206, bta-mir-211, bta-mir-212, bta-mir-223, bta-mir-26a-1, bta-mir-29d, bta-mir-30f, bta-mir-338, bta-mir-33a, bta-mir-33b, bta-mir-375, bta-mir-429, bta-mir-451, bta-mir-92a-1, bta-mir-92b, bta-mir-29e, bta-mir-29b-1, bta-mir-181a-1, bta-mir-181b-1, ssc-mir-133a-1, ssc-mir-1, ssc-mir-146b, ssc-mir-181a-1, ssc-mir-30a, bta-mir-199c, ssc-mir-206, ssc-let-7a-1, ssc-let-7e, ssc-let-7g, ssc-mir-133b, ssc-mir-29a, ssc-mir-30d, ssc-mir-30e, ssc-mir-199a-2, ssc-mir-499, ssc-mir-143, ssc-mir-10a, ssc-mir-10b, ssc-mir-103-2, ssc-mir-181a-2, ssc-mir-181b-1, ssc-mir-181d, ssc-mir-99a, ssc-mir-92a-2, ssc-mir-92a-1, ssc-mir-92b, ssc-mir-192, ssc-mir-142, ssc-mir-127, ssc-mir-202, ssc-mir-129a, ssc-mir-455, ssc-mir-125b-1, ssc-mir-338, ssc-mir-133a-2, ssc-mir-146a, bta-mir-26c, ssc-mir-30c-1, ssc-mir-126, ssc-mir-199a-1, ssc-mir-451, ssc-let-7a-2, ssc-mir-129b, ssc-mir-429, ssc-let-7d, ssc-let-7f-2, ssc-mir-132, ssc-mir-138, ssc-mir-144, ssc-mir-190a, ssc-mir-212, bta-mir-133c, ssc-mir-26b, ssc-mir-200b, ssc-mir-223, ssc-mir-375, ssc-mir-33b
In humans, the high expression of miR-129 in ovaries is associated with the control of cell growth and differentiation in the final process of ovary maturation through downregulation of its target mRNAs, whereas miR-29 expression levels, which progressively increase throughout oogenesis, may also be important (Sirotkin et al., 2009). [score:10]
microRNA-29, a key regulator of collagen expression in systemic sclerosis. [score:4]
By contrast, the miR-29 and miR-129 families showed significantly increased expression in ovaries compared to testes (Xiao et al., 2014). [score:2]
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. [score:2]
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5
[+] score: 18
CAV2 expression was upregulated in DSP-TP; this gene was the target of miR-29b and miR-122, which hadapproximately seven- and fivefold lower expression in the DSP-TP than in the LL-YY, respectively. [score:10]
The expressions of five genes (IRS1, CARNS1, MYOZ2, ANKRD2, and PLIN2) and four miRNAs (miR-4332, miR-451, miR-196a, and miR-29b) were significantly different between the DSP and the YY (S5 and S6 Figs). [score:3]
Some DE miRNAs, such as miR-29b, miR-122, miR-145-5p, let-7c, miR-4332, miR-182, miR-92b-3p, miR-29c,let-7a, and let-7e, and some DEGs such as CAV2, MYOZ2, FRZB, FASN, SCD, ESR1, and ADORA1, may be factors in the regulation of muscle growth and lipid deposition. [score:2]
Therefore, we determined that the genes CAV2, MYOZ2, and FRZB and the miRNAs miR-29b, miR-122, miR-145-5p, and miR-let-7c are the key candidates for regulating muscle growth. [score:2]
Based on the fold change, the top five were miR-4332 (FC = 0.024), miR-29b (FC = 0.140), miR-92b-3p (FC = 0.183), miR-362 (FC = 5.406), and miR-122 (FC = 0.193). [score:1]
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6
[+] score: 16
In addition, the miR-29 family is associated with the up-regulation of the tumor suppressor p53, which is central to many cellular stress responses and for inducing apoptosis [31]. [score:6]
The second group, e. g. ; the miR-29 family (containing miR-29a –b –c) and miR-22, miR-24, miR-27b and miR-142-5p showed increasing expression with age progression, with a particularly high expression in the adult tissues. [score:5]
Therefore, it is plausible that miRNAs prominently expressed at this time (for instance miR-24 and the miR-29 family members) might regulate this process. [score:4]
The miR-29 family (miR-29a, miR-29b and miR-29c) has previously been shown to be effective biomarkers of radiation -induced brain responses [29]. [score:1]
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7
[+] score: 15
There were 17 DEMs, represented by miR-124 and miR-214, dominating the miRNA-regulated gene expression in the early metaphase of embryonic stage and 10 DEMs, miR-29 for instance, were highly expressed at the postnatal stage. [score:6]
Maurer B. Stanczyk J. Jungel A. Akhmetshina A. Trenkmann M. Brock M. Kowal-Bielecka O. Gay R. E. Michel B. A. Distler J. H. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis Arthritis Rheumatol. [score:3]
Our results were consistent with previous studies, which demonstrated miR-29 targeting to the collagen family members such as COL4A1, COL1A2 and COL1A1 at ADU time points, miR-148 to the MITF and EIF4BP2 genes at early embryonic stage, and miR-487 to the IRS1 gene at the middle stage [23, 24]. [score:3]
Three category patterns from the DEMs were clustered based on the expression percentages including early-middle embryonic stage from miR-124 to miR-424, late embryonic stage from miR-345 to miR-451 and adult stage from miR-29b to miR-133a, respectively. [score:3]
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8
[+] score: 10
Secondly, targets for a sub-set of down-regulated miR (miR-15, miR-16, miR-27, miR-29, miR-34 and miR-106), of which 44 targets were identified based on our previous criteria were predicted (see Additional file 4). [score:8]
These miR have been implicated in multiple cellular processes including cell growth (miR-24), apoptosis (miR-16, miR-24 and miR-29), and cell cycle regulation in normal (miR-16) and cancerous cells (miR-24, miR-27, miR-29 and miR-34) [9, 40- 46]. [score:2]
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9
[+] score: 9
Only 27 miRNAs followed the same expression profile in both approaches, and 11 of them where DE in both groups: 4 miRNAs (miR-26b-5p, miR-29b-2-5p, miR-450b-5p and miR-450c-5p) were only expressed in infected groups and the remaining 7 miRNAs (let-7b-3p, miR-193b, miR-345-5p, miR-1306-5p, miR-2779, miR-2898 and miR-4286) were more expressed in mock-infected or healthy group, although all of them were expressed at low levels (CN<100) in both profiles. [score:9]
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10
[+] score: 7
MicroRNAs like miR-29a and miR-32 have been found to repress the expression of viral mRNAs by possible recognition and targeting of viral nucleic acids with miR-29 specifically targeting HIV-1 3’UTR region [11], [12]. [score:7]
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11
[+] score: 7
BAG3 also downregulates the microRNA-29b which leads to upregulation of the anti-apoptosis protein Mcl-l leading to resistance to anticancer drugs [110]. [score:7]
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12
[+] score: 7
Of the differentially expressed miRNAs six (miR-30a-3p, miR-132, miR-27b*, miR-29b, miR-146a and miR-9-2) were altered at more than one time point in PRRSV-infected macrophages (Figure 1). [score:3]
A total of forty cellular miRNAs were differentially expressed in PRRSV infected macrophages, six of which (miR-30a-3p, miR-132, miR-27b*, miR-29b, miR-146a and miR-9-2) were altered at more than one time point (Figure 1). [score:3]
Among these six miRNA, miR-30a-3p, miR-132, miR-27b*, miR-29b, miR-146a and miR-9-2, were altered at more than one time point. [score:1]
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13
[+] score: 7
Only four miRNAs (hsa-miR-223-5p, ssc-miR-31, ssc-miR-29a, and ssc-miR-182) were differentially expressed at 24 h pi, whereas 10 miRNAs were differentially expressed at 72 h pi (ssc-miR-29b, hsa-miR-203a-3p, hsa-miR-449a, ssc-miR-21, ssc-miR-29a, hsa-miR-23a-3p, ssc-miR-23b, ssc-miR-30c-5p, ssc-miR-423-5p, and hsa-miR-150-5p). [score:5]
The miR-29 family is well characterised and commonly described to be involved in cancers as tumor suppressors 49. [score:1]
However, the highest number of significantly regulated miRNAs compared to before challenge was found at 14d pi, at which time point the infection had completely cleared (ssc-miR-15a, ssc-miR-29b, ssc-miR-29a, hsa-miR-449a, ssc-miR-186, ssc-miR-22-5p, ssc-miR-28-5p, hsa-miR-203a-3p, ssc-miR-146a-5p, hsa-miR-150-5p, ssc-miR-23b, hsa-miR-223-3p, hsa-miR-23a-3p, hsa-miR-16-5p). [score:1]
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14
[+] score: 7
For example, miR-29, miR-181 and miR-148a can promote myoblast differentiation by inhibiting the expression of downstream target genes Akt3, Hox-A1 and ROCK1 at protein levels [10– 12]. [score:7]
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15
[+] score: 6
In addition to tissue-specific ageing, it is increasingly evident that many miRNA regulate gene expressions in well-known ageing pathways, most notably in the p53 tumor suppressor pathway (miR-34, miR-29 and miR-217, etc. ) [score:6]
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16
[+] score: 6
Another gene family that we evidenced prevalently expressed in the WBCs is mir-29 (mir-29a, mir-29b, mir-29c; p = 2.19 E-4). [score:3]
We found that miRNAs with higher expression in WBCs includes different miRNA families: mir-15, mir-17, mir-181, mir-23, mir-27 and mir-29 families. [score:3]
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17
[+] score: 5
Also, overexpression of miR-29 promotes myogenic differentiation in C2C12 cells, due to the reduction in TGF-beta, which inhibits differentiation 42. [score:5]
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18
[+] score: 5
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-27a, hsa-mir-29a, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-199a-1, hsa-mir-208a, hsa-mir-148a, hsa-mir-10a, hsa-mir-181a-2, hsa-mir-181c, hsa-mir-199a-2, hsa-mir-181a-1, hsa-mir-214, hsa-mir-221, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-23b, hsa-mir-27b, hsa-mir-125b-1, hsa-mir-128-1, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-143, hsa-mir-125b-2, hsa-mir-126, hsa-mir-127, hsa-mir-206, hsa-mir-1-1, hsa-mir-128-2, hsa-mir-29c, hsa-mir-26a-2, hsa-mir-378a, hsa-mir-148b, hsa-mir-133b, hsa-mir-424, ssc-mir-125b-2, ssc-mir-148a, ssc-mir-23a, ssc-mir-24-1, ssc-mir-26a, ssc-mir-29b-1, ssc-mir-181c, ssc-mir-214, ssc-mir-27a, ssc-let-7c, ssc-let-7f-1, ssc-let-7i, ssc-mir-103-1, ssc-mir-128-1, ssc-mir-29c, hsa-mir-486-1, hsa-mir-499a, hsa-mir-503, hsa-mir-411, hsa-mir-378d-2, hsa-mir-208b, hsa-mir-103b-1, hsa-mir-103b-2, ssc-mir-17, ssc-mir-221, ssc-mir-133a-1, ssc-mir-1, ssc-mir-503, ssc-mir-181a-1, ssc-mir-206, ssc-let-7a-1, ssc-let-7e, ssc-let-7g, ssc-mir-378-1, ssc-mir-133b, ssc-mir-29a, ssc-mir-199a-2, ssc-mir-128-2, ssc-mir-499, ssc-mir-143, ssc-mir-10a, ssc-mir-486-1, ssc-mir-103-2, ssc-mir-181a-2, ssc-mir-27b, ssc-mir-24-2, ssc-mir-23b, ssc-mir-148b, ssc-mir-208b, ssc-mir-424, ssc-mir-127, ssc-mir-125b-1, hsa-mir-378b, hsa-mir-378c, ssc-mir-411, ssc-mir-133a-2, ssc-mir-126, ssc-mir-199a-1, ssc-mir-378-2, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-499b, ssc-let-7a-2, ssc-mir-486-2, hsa-mir-378j, ssc-let-7d, ssc-let-7f-2, hsa-mir-486-2, ssc-mir-378b
Exceptions were some previously reported muscle-related miRNAs such as miR-181c/d-5p, miR-29b/c, miR-221/222 and miR-208, all of which expressed at a very low level (average RPM <100). [score:3]
PLOS ONE 7. 122 van Rooij E, Sutherland LB, Thatcher JE, DiMaio JM, Naseem RH et al. (2008) Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. [score:2]
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19
[+] score: 5
The up-regulation of miR-141, miR-200a, miR-200c, miR-26a, and miR-29 we detected were also accordant either with mice or with humans. [score:4]
Bak et al. reported 8 miRNAs (mir-7, mir-7b, mir-375, mir-141, mir-200a, mir-200c, mir-25and mir-152) with more than 3-fold enrichment in the pituitary of adult mice in a profile of the miRNAs in the central nervous system [36]; and Farh et al. and Landgraf et al. reported 6 (mir-7, mir-212, mir-26a, mir-191, mir-375 and mir-29) when comparing the miRNAs in normal and tumor pituitary cells [37], [38]. [score:1]
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20
[+] score: 5
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-29a, hsa-mir-30a, hsa-mir-31, hsa-mir-99a, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-16-2, hsa-mir-192, hsa-mir-148a, hsa-mir-10b, hsa-mir-181a-2, hsa-mir-181a-1, hsa-mir-215, hsa-mir-223, hsa-mir-224, hsa-mir-200b, hsa-mir-15b, hsa-mir-27b, hsa-mir-125b-1, hsa-mir-141, hsa-mir-143, hsa-mir-152, hsa-mir-125b-2, hsa-mir-126, hsa-mir-146a, hsa-mir-184, hsa-mir-200c, hsa-mir-155, hsa-mir-29c, hsa-mir-200a, hsa-mir-99b, hsa-mir-296, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-378a, hsa-mir-342, hsa-mir-148b, hsa-mir-451a, ssc-mir-125b-2, ssc-mir-148a, ssc-mir-15b, ssc-mir-184, ssc-mir-224, ssc-mir-23a, ssc-mir-24-1, ssc-mir-26a, ssc-mir-29b-1, ssc-let-7f-1, ssc-mir-103-1, ssc-mir-21, ssc-mir-29c, hsa-mir-486-1, hsa-mir-499a, hsa-mir-671, hsa-mir-378d-2, bta-mir-26a-2, bta-mir-29a, bta-let-7f-2, bta-mir-103-1, bta-mir-148a, bta-mir-16b, bta-mir-21, bta-mir-499, bta-mir-99a, bta-mir-125b-1, bta-mir-126, bta-mir-181a-2, bta-mir-27b, bta-mir-31, bta-mir-15b, bta-mir-215, bta-mir-30e, bta-mir-148b, bta-mir-192, bta-mir-200a, bta-mir-200c, bta-mir-23a, bta-mir-29b-2, bta-mir-29c, bta-mir-10b, bta-mir-24-2, bta-mir-30a, bta-mir-200b, bta-let-7a-1, bta-mir-342, bta-let-7f-1, bta-let-7a-2, bta-let-7a-3, bta-mir-103-2, bta-mir-125b-2, bta-mir-15a, bta-mir-99b, hsa-mir-664a, ssc-mir-99b, hsa-mir-103b-1, hsa-mir-103b-2, ssc-mir-15a, ssc-mir-16-2, ssc-mir-16-1, bta-mir-141, bta-mir-143, bta-mir-146a, bta-mir-152, bta-mir-155, bta-mir-16a, bta-mir-184, bta-mir-24-1, bta-mir-223, bta-mir-224, bta-mir-26a-1, bta-mir-296, bta-mir-29d, bta-mir-378-1, bta-mir-451, bta-mir-486, bta-mir-671, bta-mir-29e, bta-mir-29b-1, bta-mir-181a-1, ssc-mir-181a-1, ssc-mir-215, ssc-mir-30a, bta-mir-2318, bta-mir-2339, bta-mir-2430, bta-mir-664a, bta-mir-378-2, ssc-let-7a-1, ssc-mir-378-1, ssc-mir-29a, ssc-mir-30e, ssc-mir-499, ssc-mir-143, ssc-mir-10b, ssc-mir-486-1, ssc-mir-152, ssc-mir-103-2, ssc-mir-181a-2, ssc-mir-27b, ssc-mir-24-2, ssc-mir-99a, ssc-mir-148b, ssc-mir-664, ssc-mir-192, ssc-mir-342, ssc-mir-125b-1, oar-mir-21, oar-mir-29a, oar-mir-125b, oar-mir-181a-1, hsa-mir-378b, hsa-mir-378c, ssc-mir-296, ssc-mir-155, ssc-mir-146a, bta-mir-148c, ssc-mir-126, ssc-mir-378-2, ssc-mir-451, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-451b, hsa-mir-499b, ssc-let-7a-2, ssc-mir-486-2, hsa-mir-664b, hsa-mir-378j, ssc-let-7f-2, ssc-mir-31, ssc-mir-671, bta-mir-378b, bta-mir-378c, hsa-mir-486-2, oar-let-7a, oar-let-7f, oar-mir-103, oar-mir-10b, oar-mir-143, oar-mir-148a, oar-mir-152, oar-mir-16b, oar-mir-181a-2, oar-mir-200a, oar-mir-200b, oar-mir-200c, oar-mir-23a, oar-mir-26a, oar-mir-29b-1, oar-mir-30a, oar-mir-99a, bta-mir-664b, chi-let-7a, chi-let-7f, chi-mir-103, chi-mir-10b, chi-mir-125b, chi-mir-126, chi-mir-141, chi-mir-143, chi-mir-146a, chi-mir-148a, chi-mir-148b, chi-mir-155, chi-mir-15a, chi-mir-15b, chi-mir-16a, chi-mir-16b, chi-mir-184, chi-mir-192, chi-mir-200a, chi-mir-200b, chi-mir-200c, chi-mir-215, chi-mir-21, chi-mir-223, chi-mir-224, chi-mir-2318, chi-mir-23a, chi-mir-24, chi-mir-26a, chi-mir-27b, chi-mir-296, chi-mir-29a, chi-mir-29b, chi-mir-29c, chi-mir-30a, chi-mir-30e, chi-mir-342, chi-mir-378, chi-mir-451, chi-mir-499, chi-mir-671, chi-mir-99a, chi-mir-99b, bta-mir-378d, ssc-mir-378b, oar-mir-29b-2, ssc-mir-141, ssc-mir-200b, ssc-mir-223, bta-mir-148d
Members of the miRNA-29 family have been shown to revert aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B (Fabbri et al., 2007). [score:3]
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. [score:2]
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[+] score: 4
Many miRNAs, such as miR-1, miR-133, miR-29, miR-214, miR-206, miR-486, miR-208b, and miR-499 were involved in the regulation of skeletal myogenesis by binding to its target genes 36, 37. [score:4]
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[+] score: 4
miR-29 negatively regulates skeletal myogenesis by targeting Ring1 and YY1 -binding protein (Rybp) [43]. [score:4]
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[+] score: 4
Wei W. He H. B. Zhang W. Y. Zhang H. X. Bai J. B. Liu H. Z. Cao J. H. Chang K. C. Li X. Y. Zhao S. H. miR-29 targets Akt3 to reduce proliferation and facilitate differentiation of myoblasts in skeletal muscle development Cell Death Dis. [score:4]
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[+] score: 4
A lecture showed that the inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes the trans-differentiation of mouse myoblasts into myofibroblasts [23]. [score:3]
In G2 (down), the most significant differences between breeds were observed at 2 dpn, when miR-29 and miR-499 showed drastic changes. [score:1]
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[+] score: 2
2009.02.038) miR-29b-3p Potential regulator of TGFB1 29 5.48E-07 −5.260 Lu et al. 2016 (10.1096/fj. [score:2]
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[+] score: 1
For example, we found that the size of ssc-miR-29b in our library is 23 (read number is 88), while the size of miR-29b in miRBase is 20 (read number is 11). [score:1]
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[+] score: 1
Other miRNAs from this paper: ssc-mir-29b-1, ssc-mir-29c, ssc-mir-29a
miR-29a-5p has been described in many species like human, bovine, mouse, but it has not been described in pigs, where the precursor miR-29 has been included in miRBase along with the mature ssc-miR-29a-3p. [score:1]
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[+] score: 1
miR-29 was decreased in dogs with ventricular tachypacing -induced congestive heart failure (CHF) and in patients with CHF or AF [28]. [score:1]
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