Stem-loop hsa-mir-31

Accession

MI0000089

Symbol

HGNC: MIR31

Description

Homo sapiens hsa-mir-31 precursor miRNA

Literature search

385 open access papers mention hsa-mir-31
(2789 sentences)

Sequence

61510 reads, 1241 reads per million, 128 experiments

ggagaggAGGCAAGAUGCUGGCAUAGCUguugaacugggaaccUGCUAUGCCAACAUAUUGCCAUcuuucc
(((((((.(((((.(((.(((((((((.(((........)))..))))))))).))).))))).)))))))

Structure

       A     G   C         -U   gaa 
ggagagg GGCAA AUG UGGCAUAGC  guu   c
||||||| ||||| ||| |||||||||  |||    
ccuuucU CCGUU UAC ACCGUAUCG  caa   u
       A     A   A         Uc   ggg 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context

chr9: 21512115-21512185 [-]

Disease association

hsa-mir-31 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-31-5p

• Accession: MIMAT0000089
• Description: Homo sapiens hsa-miR-31-5p mature miRNA
• Sequence: 8 - AGGCAAGAUGCUGGCAUAGCU - 28
• Evidence: experimental ; cloned [1-3], Northern [1]

Mature hsa-miR-31-3p

• Accession: MIMAT0004504
• Description: Homo sapiens hsa-miR-31-3p mature miRNA
• Sequence: 44 - UGCUAUGCCAACAUAUUGCCAU - 65
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 11679670
   Identification of novel genes coding for small expressed RNAs
   "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
   "Science (2001) 294:853-858


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043