Stem-loop hsa-mir-107

Accession

MI0000114

Symbol

HGNC: MIR107

Description

Homo sapiens hsa-mir-107 precursor miRNA mir-103

Gene
family

RF00129; mir-103

Literature search

185 open access papers mention hsa-mir-107
(941 sentences)

Sequence

4415819 reads, 14654 reads per million, 155 experiments

cucucugcuuucagcuucuuuacaguguugccuuguggcauggaguucaAGCAGCAUUGUACAGGGCUAUCAaagcacaga
.(((.((((((.((((.((.(((((((((((.(((.(((.....))))))))))))))))).))))))...)))))).)))

Structure

c   c      --c    u  u           c   u   a 
 ucu ugcuuu   agcu cu uacaguguugc uug ggc u
 ||| ||||||   |||| || ||||||||||| ||| ||| g
 aga acgaaA   UCGG GA AUGUUACGACG Aac uug g
-   c      CUA    -  C           -   -   a 

Annotation confidence High

Comments

This miRNA was identified by homology to miR-103 [1], and later verified by cloning in human [2].

Genome context

chr10: 89592747-89592827 [-]

Disease association

hsa-mir-107 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-107

• Accession: MIMAT0000104
• Description: Homo sapiens hsa-miR-107 mature miRNA
• Sequence: 50 - AGCAGCAUUGUACAGGGCUAUCA - 72
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 11914277
   miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
   "Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G"
   "Genes Dev (2002) 16:720-728