Stem-loop mmu-mir-101a

Accession

MI0000148

Symbol

MGI: Mir101a

Description

Mus musculus mmu-mir-101a precursor miRNA mir-101

Gene
family

RF00253; mir-101

Literature search

129 open access papers mention mmu-mir-101a
(890 sentences)

Sequence

1299844 reads, 2337 reads per million, 107 experiments

aggcugcccuggcUCAGUUAUCACAGUGCUGAUGCuguccauucuaaaggUACAGUACUGUGAUAACUGAAggauggcagcca
.(((((((.....((((((((((((((((((.((((............)))))))))))))))))))))).....))))))).

Structure

a       cuggc                  A    gucca 
 ggcugcc     UCAGUUAUCACAGUGCUG UGCu     u
 |||||||     |||||||||||||||||| ||||      
 ccgacgg     AGUCAAUAGUGUCAUGAC AUgg     u
a       uaggA                  -    aaauc 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chr4: 101346945-101347027 [-]

Mature mmu-miR-101a-5p

• Accession: MIMAT0004526
• Description: Mus musculus mmu-miR-101a-5p mature miRNA
• Sequence: 14 - UCAGUUAUCACAGUGCUGAUGC - 35
• Evidence: experimental ; cloned [3], Illumina [4-5]

Mature mmu-miR-101a-3p

• Accession: MIMAT0000133
• Description: Mus musculus mmu-miR-101a-3p mature miRNA
• Sequence: 51 - UACAGUACUGUGAUAACUGAA - 71
• Evidence: experimental ; cloned [1-3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


3. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009