miRBase entry: mmu-mir-125a

Stem-loop mmu-mir-125a


Accession
MI0000151
Symbol
MGI: Mir125a
Description
Mus musculus mmu-mir-125a precursor miRNA
Gene family
MIPF0000033; mir-10

Literature search
198 open access papers mention mmu-mir-125a
(1294 sentences)

Sequence

2388628 reads, 4434 reads per million, 105 experiments
cugggUCCCUGAGACCCUUUAACCUGUGAggacguccagggucACAGGUGAGGUUCUUGGGAGCCugg
((((((.(((((((.((((..((((((((...(.....)..)))))))))))).))))))).))))))

Structure
      C       C    UA        gga g 
cugggU CCUGAGA CCUU  ACCUGUGA   c u
|||||| ||||||| ||||  ||||||||   | c
gguCCG GGGUUCU GGAG  UGGACAcu   g c
      A       U    --        -gg a 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chr17: 17830812-17830879 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from mmu-mir-125a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-125a-5p

Accession MIMAT0000135
Description Mus musculus mmu-miR-125a-5p mature miRNA
Sequence 6 - UCCCUGAGACCCUUUAACCUGUGA - 29
Evidence experimental
cloned [1-2], Illumina [3-4]
Database links
Predicted targets

Mature mmu-miR-125a-3p

Accession MIMAT0004528
Description Mus musculus mmu-miR-125a-3p mature miRNA
Sequence 44 - ACAGGUGAGGUUCUUGGGAGCC - 65
Evidence experimental
cloned [2], Illumina [3-4]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009