miRBase entry: mmu-mir-130a

Stem-loop mmu-mir-130a


Accession
MI0000156
Symbol
MGI: Mir130a
Description
Mus musculus mmu-mir-130a precursor miRNA
Gene family
MIPF0000034; mir-130

Literature search
90 open access papers mention mmu-mir-130a
(645 sentences)

Sequence

190612 reads, 1739 reads per million, 106 experiments
gaGCUCUUUUCACAUUGUGCUACUgucuaacguguaccgagCAGUGCAAUGUUAAAAGGGCAUc
..((((((((.((((((((((.((...............)).)))))))))).))))))))...

Structure
-ga        C          A  gucuaa 
   GCUCUUUU ACAUUGUGCU CU      c
   |||||||| |||||||||| ||      g
   CGGGAAAA UGUAACGUGA ga      u
cUA        U          C  gccaug 


Annotation confidence High
Do you think this miRNA is real?
Comments
This sequence was named miR-130 in reference [1], but is renamed here to avoid confusion with miR-130b (MIR:MI0000408).

Genome context
chr2: 84741115-84741178 [-]

Database links

Mature mmu-miR-130a-5p

Accession MIMAT0016983
Description Mus musculus mmu-miR-130a-5p mature miRNA
Sequence 3 - GCUCUUUUCACAUUGUGCUACU - 24
Evidence experimental
Illumina [8]
Database links
Predicted targets

Mature mmu-miR-130a-3p

Accession MIMAT0000141
Description Mus musculus mmu-miR-130a-3p mature miRNA
Sequence 42 - CAGUGCAAUGUUAAAAGGGCAU - 63
Evidence experimental
cloned [1-2,4-6], Northern [2], Illumina [7]
Database links
Predicted targets

References

  1. PubMed ID: 12554860
    Numerous microRNPs in neuronal cells containing novel microRNAs
    "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
    "RNA (2003) 9:180-186

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358

  4. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  5. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230

  6. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  7. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  8. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009