Stem-loop sequence ath-MIR168a

AccessionMI0000210 (change log)
DescriptionArabidopsis thaliana miR168a stem-loop
Gene family MIPF0000081; MIR168
Literature search

29 open access papers mention ath-MIR168a
(83 sentences)

Stem-loop 
       a   -  c  g      c          u     a       ggcugacacagccucgugacuuu 
5' cacc ucg gg uc gauucg uuggugcagg cggga ccaauuc                       u
   |||| ||| || || |||||| |||||||||| ||||| |||||||                        
3' gugg agc cc ag cuaagu aacuacguuc gcccu gguuagg                       a
       -   u  u  g      c          c     a       gacgaguguuugguuauuuccaa
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Confidence Annotation confidence: not enough data
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Comments

MIR168a thought to target mRNAs coding for Argonaute (AGO1), which is required for axillary shoot meristem formation and leaf development in Arabidopsis. It has been suggested that AGO1 may also influence miRNA accumulation in plants and that miR168 may act as a negative-feedback mechanism for controlling expression of the AGO1 gene [2].

Genome context
Coordinates (TAIR10; GCA_000001735.1) Overlapping transcripts
chr4: 10578635-10578772 [+]
intergenic
Database links

Mature sequence ath-miR168a-5p

Accession MIMAT0000198
Previous IDsath-miR168a
Sequence

18 -  

ucgcuuggugcaggucgggaa

 - 38

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Evidence experimental; cloned [1,3], Northern [1], 454 [4-5], MPSS [4], Illumina [6]

Mature sequence ath-miR168a-3p

Accession MIMAT0031884
Sequence

103 -  

cccgccuugcaucaacugaau

 - 123

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Evidence not experimental

References

1
PMID:12101121 "MicroRNAs in plants" Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP Genes Dev. 16:1616-1626(2002).
2
PMID:12202040 "Prediction of plant microRNA targets" Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP Cell. 110:513-520(2002).
3
PMID:16040653 "Expression of Arabidopsis MIRNA genes" Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC Plant Physiol. 138:2145-2154(2005).
4
PMID:16954541 "MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent RNA polymerase-2 mutant" Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS, Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC Genome Res. 16:1276-1288(2006).
5
PMID:17182867 "A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana" Rajagopalan R, Vaucheret H, Trejo J, Bartel DP Genes Dev. 20:3407-3425(2006).
6
PMID:19815687 "Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in Arabidopsis" Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW J Exp Bot. 61:165-177(2010).