miRBase entry: mmu-mir-181a-2

Stem-loop mmu-mir-181a-2


Accession
MI0000223
Symbol
MGI: Mir181a-2
Description
Mus musculus mmu-mir-181a-2 precursor miRNA
Gene family
MIPF0000007; mir-181

Literature search
206 open access papers mention mmu-mir-181a-2
(1787 sentences)

Sequence

4245388 reads, 7023 reads per million, 107 experiments
ccauggAACAUUCAACGCUGUCGGUGAGUuugggauucaaaaacaaaaaaACCACCGACCGUUGACUGUACCuugg
(((.((.(((.((((((..(((((((.((((.................))))))))))))))))).))).)).)))

Structure
   u  A   U      CU       A    gggauuc 
cca gg ACA UCAACG  GUCGGUG GUuu       a
||| || ||| ||||||  ||||||| ||||       a
ggu CC UGU AGUUGC  CAGCCAC CAaa       a
   u  A   C      --       -    aaaacaa 


Annotation confidence High
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Genome context
chr2: 38852735-38852810 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from mmu-mir-181a-2
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-181a-5p

Accession MIMAT0000210
Description Mus musculus mmu-miR-181a-5p mature miRNA
Sequence 7 - AACAUUCAACGCUGUCGGUGAGU - 29
Evidence experimental
cloned [2,4], Illumina [5-6]
Database links
Predicted targets

Mature mmu-miR-181a-2-3p

Accession MIMAT0005443
Description Mus musculus mmu-miR-181a-2-3p mature miRNA
Sequence 51 - ACCACCGACCGUUGACUGUACC - 72
Evidence experimental
cloned [5], Illumina [6-7]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12624257
    Vertebrate microRNA genes
    "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
    "Science (2003) 299:1540

  3. PubMed ID: 12554859
    New microRNAs from mouse and human
    "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
    "RNA (2003) 9:175-179

  4. PubMed ID: 15538371
    A pancreatic islet-specific microRNA regulates insulin secretion
    "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
    "Nature (2004) 432:226-230

  5. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  6. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  7. PubMed ID: 15634332
    New human and mouse microRNA genes found by homology search
    "Weber MJ"
    "FEBS J (2005) 272:59-73