miRBase entry: hsa-mir-30d

Stem-loop hsa-mir-30d


Accession
MI0000255
Symbol
HGNC: MIR30D
Description
Homo sapiens hsa-mir-30d precursor miRNA
Gene family
MIPF0000005; mir-30

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR30D is a microRNA that has been studied in various contexts [PMC5372318]. In a study of cutaneous squamous cell carcinoma (CSCC) patients, the copy number variations (CNVs) of MIR30D were examined in both cancer tissues and adjacent normal tissues (ANTs) [PMC5372318]. MIR30D has been identified as a key regulator of human adipocyte development [PMC5701175]. Additionally, elevated expression of MIR30D and miR126 has been observed in patients with chronic total occlusion (CTO) compared to healthy individuals [PMC4558025].

Literature search
380 open access papers mention hsa-mir-30d
(1570 sentences)

Sequence

1132297 reads, 2889 reads per million, 157 experiments
guuguUGUAAACAUCCCCGACUGGAAGcuguaagacacagcuaagCUUUCAGUCAGAUGUUUGCUGCuac
...((.(((((((((...(((((((((((..............))))))))))).))))))))).))...

Structure
guu  U         CCC           guaaga 
   gu GUAAACAUC   GACUGGAAGcu      c
   || |||||||||   |||||||||||       
   CG CGUUUGUAG   CUGACUUUCga      a
cau  U         --A           aucgac 


Annotation confidence High
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Genome context
chr8: 134804876-134804945 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-30d
Name Accession Chromosome Start End Strand Confidence




Database links

Mature hsa-miR-30d-5p

Accession MIMAT0000245
Description Homo sapiens hsa-miR-30d-5p mature miRNA
Sequence 6 - UGUAAACAUCCCCGACUGGAAG - 27
Evidence experimental
cloned [2-4]
Database links
Predicted targets

Mature hsa-miR-30d-3p

Accession MIMAT0004551
Description Homo sapiens hsa-miR-30d-3p mature miRNA
Sequence 46 - CUUUCAGUCAGAUGUUUGCUGC - 67
Evidence experimental
cloned [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  3. PubMed ID: 17989717
    Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis
    "Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O, Rovira C, Naya H, Dighiero G, Cayota A"
    "Leukemia (2008) 22:330-338

  4. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739