miRBase entry: hsa-mir-204

Stem-loop hsa-mir-204


Accession
MI0000284
Symbol
HGNC: MIR204
Description
Homo sapiens hsa-mir-204 precursor miRNA
Gene family
MIPF0000042; mir-204

Literature search
191 open access papers mention hsa-mir-204
(1578 sentences)

Sequence

23274 reads, 816 reads per million, 110 experiments
ggcuacagucuuucuucaugugacucguggacUUCCCUUUGUCAUCCUAUGCCUgagaauauaugaaggagGCUGGGAAGGCAAAGGGACGUucaauugucaucacuggc
.....((((..........(((((...(((((.((((((((((.(((((.((((...............))))))))).)))))))))).)))))...))))).))))..

Structure
ggcua    cuuucuucau     ucg     U          A     U    gagaau 
     cagu          gugac   uggac UCCCUUUGUC UCCUA GCCU      a
     ||||          |||||   ||||| |||||||||| ||||| ||||      u
     guca          uacug   acuUG AGGGAAACGG AGGGU CGga      a
---cg    ---------c     uua     C          A     -    ggaagu 


Annotation confidence High
Do you think this miRNA is real?
Comments
This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences [1]. Expression of the excised miR has been validated in zebrafish, and the ends mapped by cloning. Landgraf et al. confirm expression in human [2].

Genome context
chr9: 70809975-70810084 [-]

Disease association
hsa-mir-204 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-204-5p

Accession MIMAT0000265
Description Homo sapiens hsa-miR-204-5p mature miRNA
Sequence 33 - UUCCCUUUGUCAUCCUAUGCCU - 54
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-204-3p

Accession MIMAT0022693
Description Homo sapiens hsa-miR-204-3p mature miRNA
Sequence 72 - GCUGGGAAGGCAAAGGGACGU - 92
Evidence not_experimental
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12624257
    Vertebrate microRNA genes
    "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
    "Science (2003) 299:1540